Core B: Biostatistics and Bioinformatics

核心B：生物统计学和生物信息学

基本信息

批准号：
10686376
负责人：
Chengcheng Hu
金额：
$ 13.94万
依托单位：
UNIVERSITY OF ARIZONA
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-10 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10686376
关键词：
Address Annual Reports Applications Grants Arizona Award Basic Science Bioinformatics Biometry Biostatistics Shared Resource Cancer Center Clinical Clinical Cancer Center Clinical Trials Clinical Trials Data Monitoring Committees Collaborations Computers Conceptions Consultations Core Grant Data Data Analyses Data Collection Databases Development Electronic Mail Ensure Faculty Financial Support Funding Goals Grant Human Resources Individual Information Retrieval Information Storage Infrastructure Journals Knowledge Manuscripts Methodology Methods National Cancer Institute Nature Pathway interactions Peer Review Phase Policies Preparation Prevention Procedures Program Research Project Grants Progress Reports Publications Quality Control Reporting Research Research Design Research Personnel Role Sample Size Schedule Services Skin Carcinoma Statistical Data Interpretation Statistical Study Universities Work data management data quality design meetings member power analysis programs technical report translational goal

项目摘要

ABSTRACT Core B (Hu, Roe) Biostatistics and Bioinformatics The goal of the Biostatistics and Bioinformatics Core is to facilitate the Targeted Prevention for Non-Melanoma Skin Cancer Program Project Grant (PPG) scientific objectives by integrating strong statistical study design, accurate and organized data, and appropriate statistical analyses and interpretation into all projects. The Biostatistics and Bioinformatics faculty and staff will be intimately involved in the conception, design, implementation, analysis, and reporting of research conducted in the PPG. Core B personnel work not only on design, data management, and analysis issues, an essential role, but also develop a logical framework for the scientific approach applied to PPG research questions and help to ensure valid interpretation of the results. The specific aims of Core B are: Aim 1. To provide statistical collaboration in the design, execution and analysis of all projects. Aim 2. To develop procedures for data collection, and to build and maintain computer databases for information storage and retrieval. Aim 3. To provide reports on individual study progress, data for the UACC Data and Safety Monitoring Board (DSMB), and reports for the Scientific Advisory Board (SAB) meetings. The Core B support activities have been combined into a single core to facilitate interactions among the biostatisticians and bioinformaticians involved in PPG projects. The interactive nature of PPG activities facilitates the involvement of both the Biostatistics and Bioinformatics personnel within the projects. The translational goal is to facilitate integration of project results among the basic science, clinical, bioinformatics, and biostatistician investigators.

抽象的核心 B（Hu、Roe）生物统计学和生物信息学生物统计学和生物信息学核心的目标是促进非黑色素瘤的针对性预防皮肤癌计划项目拨款 (PPG) 通过整合强大的统计研究设计实现科学目标，准确且有组织的数据，以及对所有项目进行适当的统计分析和解释。这生物统计学和生物信息学教职员工将密切参与概念、设计、 PPG 中进行的研究的实施、分析和报告。核心B人员的工作不仅限于设计、数据管理和分析问题，发挥着至关重要的作用，而且还为科学方法应用于 PPG 研究问题，有助于确保结果的有效解释。核心 B 的具体目标是：目标 1. 在所有项目的设计、执行和分析中提供统计协作。目标 2. 开发数据收集程序，并建立和维护计算机数据库信息存储和检索。目标 3. 提供个人研究进展、UACC 数据和安全监测数据的报告委员会 (DSMB) 以及科学顾问委员会 (SAB) 会议的报告。核心 B 支持活动已合并为一个核心，以促进各部门之间的互动参与 PPG 项目的生物统计学家和生物信息学家。 PPG活动的互动性促进生物统计学和生物信息学人员参与项目。这转化目标是促进基础科学、临床、生物信息学、和生物统计学家研究人员。