2023 RNA Editing Gordon Research Conference and Gordon Research Seminar

2023年RNA编辑戈登研究大会暨戈登研究研讨会

基本信息

批准号：
10683612
负责人：
PETER A. BEAL
金额：
$ 0.95万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-03-15 至 2024-03-14
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10683612
关键词：
Asia Autoimmune Diseases Biochemistry Biological Models Biological Process Canada Cellular biology Chemicals Cognition Collaborations Cytosine DNA DNA Modification Process Data Deaminase Dedications Defect Detection Development Engineering Enzymes Epigenetic Process Europe Faculty Female Fostering Gene Expression Genes Genetic Diseases Goals Health Health Sciences Hour Human Industry International Knowledge Malignant Neoplasms Mentorship Modification Natural Immunity Notification Nucleic Acids Nucleosides Postdoctoral Fellow Protein Biosynthesis RNA RNA Editing Renaissance Research Research Personnel Rest Saskatchewan Science Scientist Student Selections Surveys Techniques Texas Therapeutic Transfer RNA Universities Uracil Woman adaptive immunity base base editor biological systems career epitranscriptomics gender equity genome editing graduate student human disease meetings next generation nucleobase posters symposium

项目摘要

Project Summary The GRC on RNA editing is the premier international meeting dedicated to nucleic acid modifications. The 2023 meeting is subtitled: “RNA/DNA editing and epitranscriptomics across biological systems”. Modifications to the common nucleosides found in DNA and RNA have been known for many years. However, recent advances in analytical techniques for their detection, along with a deeper understanding of the broad impact these modifications have on fundamental biological processes, including human disease, have caused a renaissance in their study. Indeed, we now know that nucleic acid modifications are common in various naturally occurring nucleic acids and influence gene expression, protein synthesis, cognition, innate and adaptive immunity, autoimmune disease and cancer. Furthermore, several research labs have repurposed enzymes that naturally edit RNA or modify DNA bases for targeted genome editing. This meeting will bring together a diverse group of scientists with varying expertise with the common goal of sharing ideas and approaches that can advance our understanding of the many facets of nucleic acid modifications. This conference has three specific aims. First, we will support the development of the next generation of scientific leaders. Key to achieving this aim is supporting the accompanying Gordon Research Seminar (GRS). In the two days preceding the GRC, a GRS will take place that is focused on the exchange of research data and ideas among graduate students and post-docs in the editing and modification field. Our second specific aim is to facilitate knowledge exchange on DNA and RNA editing and modification. During the five day GRC, there is approximately four hours in each afternoon for networking, there are four poster sessions, 46 speakers and 6 speakers selected from abstracts covering all aspects of DNA and RNA editing research to foster interdisciplinary and collaborative interactions. Our third aim is to connect academic researchers to stakeholders in industry. Representatives of gene editing companies and biomedical science companies with an editing/modification focus will participate in the 2023 conference. This interaction will facilitate collaboration with companies or other labs that can take basic health related research to the next level of developing treatments for genetic diseases.

项目概要 RNA 编辑 GRC 是致力于核酸修饰的首要国际会议。 2023 年会议的副标题是：“跨生物系统的 RNA/DNA 编辑和表观转录组学”。 DNA 和 RNA 中常见的核苷已为人们所知很多年了，然而，最近才为人所知。检测分析技术的进步，以及对其广泛影响的更深入了解这些改变对包括人类疾病在内的基本生物过程产生了影响事实上，我们现在知道核酸修饰在各种疾病中都很常见。天然存在的核酸并影响基因表达、蛋白质合成、认知、先天和此外，一些研究实验室已经改变了用途。本次会议将带来自然编辑RNA或修饰DNA碱基以进行靶向基因组编辑的酶。将拥有不同专业知识的多元化科学家聚集在一起，共同目标是分享想法和可以增进我们对核酸修饰的许多方面的理解的方法。会议有三个具体目标：首先，我们将支持下一代科学的发展。实现这一目标的关键是支持随之而来的戈登研究研讨会（GRS）。 GRC 举行前两天，将举行 GRS，重点是研究数据的交流和我们的第二个具体目标是编辑和修改领域的研究生和博士后的想法。为了促进 DNA 和 RNA 编辑和修饰方面的知识交流，在为期五天的 GRC 期间，有每天下午大约四个小时的交流时间，有四场海报会议、46 位演讲者和 6 位演讲者。从摘要中选出的演讲者涵盖 DNA 和 RNA 编辑研究的各个方面，以促进我们的第三个目标是将学术研究人员与跨学科和协作互动联系起来。基因编辑公司和生物医学科学公司的利益相关者。编辑/修改焦点将参加 2023 年会议，这种互动将促进合作。与能够将基础健康相关研究提升到新发展水平的公司或其他实验室合作遗传疾病的治疗。