FASEB SRC Calcium and Cell Function 2023

FASEB SRC 钙和细胞功能 2023

• 批准号: 10681799
• 负责人: Mohamed Trebak
• 金额: $ 0.5万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10681799
• 关键词: Acceleration; Address; Affect; Arrhythmia; Asia; Asthma; Biological Process; Biology; Biomedical Research; Blood Vessels; Brazil; COVID-19; COVID-19 outbreak; Calcium; Calcium Signaling; Canada; Cardiovascular Diseases; Cardiovascular Physiology; Cardiovascular system; Cell physiology; Cells; Cessation of life; China; Collaborations; Defect; Development; Disabled Persons; Discipline; Disease; Drosophila genus; Europe; Explosion; Fees; Fertilization; Financial Support; Fostering; Funding; Future; Gene Expression; General Population; Goals; Grant; Health; Heart; Human; Hypertension; Immune; Immune response; Immune system; Immunologic Deficiency Syndromes; India; International; Japan; Lead; Life; Medical center; Membrane; Mentors; Methods; Mitochondria; Molecular; Muscle Contraction; Nervous System; Optics; Organ; Pathology; Pathway interactions; Physiological; Physiological Processes; Physiology; Piezo ion channels; Play; Population; Portugal; Postdoctoral Fellow; Proteins; Rare Diseases; Regulation; Research; Research Personnel; Role; Science; Scientist; Second Messenger Systems; Signal Pathway; Signal Transduction; Signaling Protein; Site; Stroke; Structure; Students; Synaptic Transmission; TYRP1 gene; Texas; Transcend; Travel; Underrepresented Minority; Universities; Vermont; Woman; Work; career; cell motility; cost; equity, diversity, and inclusion; in vivo; insight; mechanotransduction; meetings; member; molecular dynamics; muscular system; nervous system disorder; neurotransmission; new technology; novel; optogenetics; posters; programs; recruit; response; single molecule; structural biology; symposium; synergism; translational scientist; virtual

Project Summary This is an application for partial support of the FASEB Science Research Conference (SRC) on Calcium and Cell Function, which will be held from June 24th – June 29th 2023 in Lisbon, Portugal. The objective of this conference is to stimulate discourse, seed new ideas, and inspire collaborations to accelerate new discoveries on calcium signaling at the basic and translational levels. Calcium is regarded as a signal for life and death, arguably one of the most ubiquitous second messengers in biology that plays indispensable roles in a myriad of biological processes, ranging from heart beating, vascular tone, muscle contraction, synaptic transmission, development, gene expression, cell migration and immune response. Defects in the calcium signal handling machinery can lead to a large number of serious diseases, including neurological disorders, immunodeficiencies, developmental defects and cardiovascular disorders (hypertension, stroke, and cardiac arrhythmia). Because of this extreme diversity of functions and pathologies, researchers working in the calcium signaling tend to present their work at different meetings with little overlap, even though there are many common mechanisms, approaches, and insights into calcium signaling that transcend these boundaries. To address this, a primary purpose of this biennial FASEB SRC is to bring together leading investigators from a diversity of fields to share the latest and most exciting developments in Calcium and Cell Function, with the aim of sharing information across disciplines, establishing new personal contacts, fostering future collaborations, and promoting diversity, equity and inclusion in biomedical research. The co-chairs of the 2023 conference will be Drs. Mohamed Trebak (University of Pittsburgh) and Yubin Zhou (Texas A&M University), as well as Drs. Jen Liou and Ilya Bezprozvanny (University of Texas Southwestern Medical Center), who are all recognized leaders in the calcium signaling field. The Program consists of nine scientific sessions, one keynote address and three special mentoring sessions. A significant portion of talks will focus upon the molecular and cellular basis of cardiovascular diseases. There will be 36 session speakers giving full talks, including 16 women (44% of speakers) and 9 session chairs (5 of whom are women, 56%). Most of the invited speakers have not presented at this conference during prior meetings. We also reserved talk slots to encourage the participation of early career stage investigators and members of under-represented minorities in science, the numbers of which will be bolstered in 9 short talks to be selected from submitted abstracts. The conference venue has appropriate facilities for disabled attendees. The topics and themes covered in this conference will be timely and highly relevant for a broad population of scientists, clinicians, and the general public.

项目概要 这是 FASEB 钙和钙科学研究会议 (SRC) 部分支持的申请 Cell Function 将于 2023 年 6 月 24 日至 29 日在葡萄牙里斯本举行 本届会议的目标。 会议旨在激发讨论、播种新想法并激发合作以加速新发现 钙信号在基础和翻译水平上被认为是生与死的信号， 可以说是生物学中最普遍的第二信使之一，在许多领域发挥着不可或缺的作用 生物过程，包括心跳、血管张力、肌肉收缩、突触传递、 发育、基因表达、细胞迁移和免疫反应的缺陷。 机械可导致大量严重疾病，包括神经系统疾病、免疫缺陷、 发育缺陷和心血管疾病（高血压、中风和心律失常）。 这种功能和病理学的极端多样性，从事钙信号传导的研究人员倾向于提出 尽管有许多共同机制，但他们在不同会议上的工作几乎没有重叠， 方法以及对超越这些界限的钙信号传导的见解。 为了解决这个问题，每两年一次的 FASEB SRC 的主要目的是汇集来自不同领域的主要研究人员 多元化领域分享钙和细胞功能的最新、最令人兴奋的进展，旨在 跨学科共享信息、建立新的个人联系、促进未来的合作，以及 促进生物医学研究的多样性、公平性和包容性。 2023 年会议的联合主席将是 Mohamed Trebak 博士（匹兹堡大学）和 Yubin Zhou（德克萨斯农工大学）以及 Jen 博士 Liou 和 Ilya Bezprozvanny（德克萨斯大学西南医学中心），都是公认的领导者 该计划由九个科学会议、一个主题演讲和三个会议组成。 特别指导会议的很大一部分将集中于分子和细胞基础。 心血管疾病将有 36 名会议发言人进行全面演讲，其中包括 16 名女性（占 44%）。 发言人）和 9 名会议主席（其中 5 名是女性，占 56%）。 在之前的会议期间，我们还预留了演讲时段，以鼓励尽早参与。 职业阶段的调查员和科学领域代表性不足的少数群体成员，其数量将 从提交的摘要中选出 9 个简短的演讲作为支撑。会议地点有合适的。 本次会议涵盖的议题和主题将是及时且高度的。 与广大科学家、人群和公众相关。