National Center on Minority Health and Health Disparities-Center

国家少数民族健康和健康差异中心

• 批准号: 8072165
• 负责人: JEROME F STRAUSS
• 金额: $ 134.94万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-10 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8072165
• 关键词: National; Center; Minority; Health; Disparities

Overall, minorities suffer a significantly higher burden of morbidity and mortality compared to whites, despite improvement of the nation's health in general over the past few decades. Across the nation, African Americans have an infant mortality rate more than twice the rate for whites. Statistics for Virginia reflect the National data. In Richmond, Virginia, African Americans suffer a disproportionate amount of adverse pregnancy outcomes, with an infant mortality rate ranging from 2 to 4 times the rate for whites from 2000- 2004. In an effort to improve pregnancy outcomes for African Americans in the Richmond area, the Virginia Commonwealth University (VCU) Center of Excellence in Health Disparities Research (CoEHDR) proposes to (1) conduct research on adverse pregnancy outcomes in African Americans, (2) stimulate new research in this area, (3) work with community stakeholders to conduct and evaluate the impact of a community health education intervention, (4) promote participation of minority populations in research (5) incorporate a research training component for minority students into community engagement/outreach efforts. To accomplish these aims, the CoEHDR will engage in the following activities. The CoEHDR will initiate three full research projects and two pilot projects in the first year of funding. Full research projects will focus on the genetics of preterm birth in African Americans, immunological responses to periodontis that may lead to premature birth, and increasing Safer Sex Skills development among pregnant women at high risk for HIV infection. Pilot projects will involve enhancing fetal exposure to antiretroviral medications and describing the geographic distribution of birth outcomes and environmental stressors. All research will focus on African American subjects, with the goals of identifying and implementing unique diagnostic and interventions that will address major health disparities. As the research pillar of VCU's Center on Health Disparities (CHD), the CoEHDR will capitalize on CHD infrastructure to stimulate research in health disparities at VCU, identifying researchers who can focus their efforts in this vital area. In addition, the CoEHDR will work with community stakeholders to conduct and evaluate the impact of a community health education intervention on healthier pregnancies. The CoEHDR will also provide research training opportunities for disparity population students, who will work with investigators on the health education intervention and other research projects.

总体而言，尽管过去几十年来，尽管美国健康的一般健康状况改善了，但少数民族的发病率和死亡率与白人相比要高得多。在全国范围内，非裔美国人的死亡率率是白人率的两倍以上。弗吉尼亚州的统计数据反映了国家数据。 In Richmond, Virginia, African Americans suffer a disproportionate amount of adverse pregnancy outcomes, with an infant mortality rate ranging from 2 to 4 times the rate for whites from 2000- 2004. In an effort to improve pregnancy outcomes for African Americans in the Richmond area, the Virginia Commonwealth University (VCU) Center of Excellence in Health Disparities Research (CoEHDR) proposes to (1) conduct research on adverse pregnancy （2）刺激该领域的新研究的结果，（3）与社区利益相关者合作进行和评估社区健康教育干预的影响，（4）促进少数群人参与研究（5），将少数群体的研究培训组成了为少数族裔学生参与社区参与/推广活动的研究。为了实现这些目标，COEHDR将从事以下活动。 COEHDR将在资金的第一年开始启动三个完整的研究项目和两个试点项目。完整的研究项目将重点关注非洲裔美国人早产的遗传学，对牙周病的免疫学反应可能导致早产，并提高患有HIV感染高风险的孕妇的更安全的性技能发展。试点项目将涉及增强胎儿接触抗逆转录病毒药物，并描述出生结果和环境压力的地理分布。所有研究都将侧重于非裔美国人主题，其目标是确定和实施将解决重大健康差异的独特诊断和干预措施。作为VCU健康差异中心（CHD）的研究支柱，COEHDR将利用CHD基础设施，以刺激VCU的健康差异研究，从而确定可以将精力集中在这一重要领域的研究人员。此外，COEHDR将与社区利益相关者合作，进行和评估社区健康教育干预对健康怀孕的影响。 COEHDR还将为差异人群学生提供研究培训机会，他们将与调查人员一起进行健康教育干预和其他研究项目。