Clinician Scientist Training Program (CSTP)

临床医生科学家培训计划 (CSTP)

• 批准号: 8248542
• 负责人: STEPHANIE S O'MALLEY
• 金额: $ 53.37万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-09-30 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8248542
• 关键词: Behavior Therapy; Clinical; Clinical Research; Development; Drug Addiction; Drug abuse; Evaluation; Faculty; Funding; Generations; Goals; Guidelines; Health Services Research; Individual; Investigation; Mentorship; Molecular Neurobiology; Pharmacological Treatment; Phase; Positioning Attribute; Psychiatry; Research; Research Methodology; Research Personnel; Research Project Grants; Research Proposals; Research Support; Research Training; Scientist; Substance abuse problem; Time; Training; Training Programs; Universities; Work; career; innovation; interest; medical schools; member; multidisciplinary; pre-clinical; programs; skills

DESCRIPTION (provided by applicant): The Division of Substance Abuse, Department of Psychiatry at Yale University School of Medicine requests a 4th 5-year renewal for our Clinician Scientist Training Program, which has been providing intensive training in research methods for clinical and translational investigation of drug abuse since 1991. Presently the Clinician Scientis Training Program supports six early career faculty members engaged in various aspects of drug abuse research. Under the new guidelines, we request support to continue to the mentorship and development of these 6 early career faculty, and, given the new guidelines, transition to supporting 3 positions during the course of the proposed five years of support. The support will permit the Clinician Scientists to spend 3-5 years at Yale's Division of Substance Abuse obtaining clinical and research training under the mentorship of a team of 37 senior investigators whose interests range from molecular neurobiology to health services research. With over 200 externally funded research projects, the central theme of our research program is the development and evaluation of innovative pharmacological and behavioral treatments for individuals with drug addictions in a manner informed by emerging neuroscientific findings. Our multidisciplinary, translational program enables us to conduct research that moves rapidly in both directions from preclinical projects ("bench") to clinical studies ("bedside"). The training goal for this program is to provide Clinician Scientist Scholars at the junior faculty level with a opportunity to devote virtually full-time effort during the initial phase of their careers to learnng research skills and conducting research projects as a critical step toward launching careers as independent research scientists. After initial work conducted with the support of this program, they will be guided to develop scientifically meritorious research proposals (using, for example, R03 and R01 mechanisms) which will provide support for research that extends beyond the period of the program. Since the onset of the program we have provided training for 29 Clinician Scientists, many of whom are among the leaders of their generation of drug abuse investigators. PUBLIC HEALTH RELEVANCE: Addictions are arguably the most costly conditions to society. Thus, investigations into new and improved treatments for addictions are of vital importance. This proposal seeks support to train early career investigators at the junior faculty level for training as clinician scientists investigating drug addiction, with a focus on treatment development.

描述（由申请人提供）：耶鲁大学医学院精神病学系的滥用司要求我们的临床科学家培训计划进行第4届5年续签，该计划一直在为临床和翻译研究的临床研究方法提供深入的培训，以自1991年以来对药物滥用的研究方法，自1991年以来。目前，临床科学培训计划支持六个早期的职业职业虐待培养精神研究。根据新的准则，我们要求支持这6个早期职业教师的指导和发展，并且鉴于新的指南，在拟议的五年支持的过程中过渡到支持3个职位。这项支持将使临床医生科学家在耶鲁大学的滥用药物滥用部门度过3 - 5年，在37名高级研究人员的指导下获得临床和研究培训，其利益从分子神经生物学到卫生服务研究。我们的研究计划的中心主题是200多个外部资助的研究项目，是针对吸毒成瘾者的创新药理学和行为治疗的开发和评估，并以新兴的神经科学发现的方式告知。我们的跨学科转化计划使我们能够进行研究，从临床前项目（“板凳”）到临床研究（“床边”），这两个方向都可以迅速发展。该计划的培训目标是在初级教师级别为临床医生的学者提供几乎全职努力的机会，以学习研究技能并进行研究项目，这是朝着独立研究科学家启动职业的关键一步。在该计划的支持下进行的初步工作后，他们将被指导开发科学的有功研究建议（例如，使用R03和R01机制），该建议将为超出计划期间的研究提供支持。自计划发作以来，我们已经为29位临床医生提供了培训，其中许多人都是滥用药物滥用研究人员的领导者。 公共卫生相关性：成瘾可以说是社会最昂贵的条件。因此，对成瘾的新治疗方法的调查至关重要。该提案寻求支持在初级教师一级培训早期职业调查员，以培训临床医生，以调查药物成瘾，重点是治疗开发。