DEVELOPMENT OF SOFTWARE FOR IMAGE ANALYSIS, DISPLAY, AND MODELING

图像分析、显示和建模软件的开发

• 批准号: 8362524
• 负责人: DAVID N MASTRONARDE
• 金额: $ 4.26万
• 依托单位: UNIVERSITY OF COLORADO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362524
• 关键词: Address; Cell physiology; Cellular Structures; Code; Computer software; Data Set; Development; Documentation; Excision; Funding; Generations; Grant; Image; Image Analysis; Linux; Methods; Modeling; National Center for Research Resources; Operating System; Principal Investigator; Research; Research Infrastructure; Resources; Roentgen Rays; Running; Source; Tomogram; United States National Institutes of Health; Work; charge coupled device camera; cost; graphical user interface; image reconstruction; programs; software development; tomography

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We have continued development and support of the IMOD software package for tomographic reconstruction and image display, modeling, and analysis. Major milestones were the first release of the eTomo graphical interface for tomogram generation (described elsewhere) and the release of fully functional versions for Microsoft Windows and Macintosh OS X operating systems. Some significant functionality was added in the past year, including a program for automatic removal of X-rays from CCD camera images, the ability to bin down images when loading them into the 3dmod display and modeling program, and other changes to facilitate working with very large data sets. We developed a new method for providing parameter input to programs, to make it easier to run them manually or from other programs such as eTomo, to allow new options to be added to programs without breaking existing code and command files, and to centralize the specification and documentation of program options. About 15 Fortran programs have been converted to the new method. There were also major improvements in documentation: a guide to 3dmod was revised and greatly expanded to provide a comprehensive introduction to the program; a guide to tomography was thoroughly revised to describe how to work through eTomo; and a tutorial for building tomograms was also released, together with a complete dual-axis data set. With the release of versions for new platforms, downloads of the software are higher than ever. For the 2 weeks after the major version release in November 2003 plus 7 weeks in February/March 2003, there were downloads from 299 distinct IP addresses, of which 49% were for Windows, 25% for Linux, 21% for Macintosh, and 5% for SGI.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 我们继续开发和支持IMOD软件包，用于层析成像和图像显示，建模和分析。 主要里程碑是eTomo图形界面的首次发行版，用于断层图生成（其他地方描述），以及Microsoft Windows和Macintosh OS X操作系统的功能性版本的发布。 在过去的一年中，添加了一些重要的功能，包括一种从CCD摄像机图像中自动删除X射线的程序，可以将图像加载到3DMOD显示屏和建模程序中时将图像放下的能力，以及其他更改以便利使用非常大的数据集。 我们开发了一种向程序提供参数输入的新方法，以使手动或从其他程序（例如etomo）运行它们，以允许将新选项添加​​到程序中而不破坏现有代码和命令文件，并集中程序选项的规范和文档。 大约15个Fortran程序已转换为新方法。 文档也有重大改进：对3DMOD的指南进行了修订，并大大扩展了该计划的全面介绍；对层析成像指南进行了彻底修订，以描述如何通过etomo工作。还发布了用于构建断层图的教程，以及完整的双轴数据集。 随着新平台版本的发布，该软件的下载比以往任何时候都更高。 在2003年11月的主要版本发布后的两个星期，加上2003年2月/3月的7周，从299个不同的IP地址下载，其中49％用于Windows，Linux为25％，Macintosh为21％，SGI为5％。