Biostatistics, Epidemiologic & Bioinformatic Training in Environmental Health

生物统计学、流行病学

• 批准号: 7629890
• 负责人: Elizabeth A Lianne Sheppard
• 金额: $ 26.57万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7629890
• 关键词: Bioinformatics; Biometry; Environmental Health; Training

DESCRIPTION (provided by applicant) The University of Washington Department of Biostatistics, with the collaboration of faculty from the Departments of Computer Sciences, Epidemiology, Genome Sciences, Medicine, Pathology, Environmental and Occupational Health Sciences, and Statistics proposes to train biostatisticians and life scientists to develop and apply quantitative methods to the environmental health sciences in a new program "Biostatistics, Epidemiologic and Bioinfomatic Training in the Environmental Health Sciences." The proposed Training Program has two pathways: one population-based and one laboratory-based. The population-based pathway will emphasize statistical methods in environmental epidemiology to elucidate the etiologies of environmentally-related diseases. The laboratory-based pathway will focus on the interpretation of modern genomic data and how they may be exploited to unravel the biological bases of these diseases. Both pathways will foster a multidisciplinary, collaborative and interdisciplinary training environment that 1) includes quantitative and applied training objectives, 2) assigns a quantitative and a scientific mentor to each trainee, 3) involves each trainee in a project that leads to expertise in multiple disciplines necessary to advance environmental health science research, 4) recruits trainees with differing backgrounds to enhance cross-training, and 5) targets training activities to enhance training goals. The investigators propose a trainee recruitment strategy that will start with four pre-doctoral and two postdoctoral trainees and build to eight pre-doctoral and four post-doctoral trainees in year five. Trainees will be recruited from multiple disciplines and each will have an individualized Training Program unified under the common theme of developing quantitative skills for application to the environmental health sciences. The pre-doctoral trainees will pursue Ph.D. degrees in biostatistics, environmental health, epidemiology, or genome sciences, whereas the postdoctoral trainees will be eligible to seek MPH or MS degrees in an appropriate discipline. These trainees will be mentored by an outstanding group of 23 faculty drawn from the collaborating departments, all of whom have substantial training and research records. The preceptors will direct the trainee's research as well as contribute to teaching their courses and providing training in the ethical conduct of research and the management of laboratory and population studies. BACKGROUND There have been substantive changes to the application since the initial submission. The description of the pre-doctoral program has been expanded to provide specific detail on the curriculum. Examples have been provided of the dual mentoring program and how it leads to program integration. The dual mentorship arrangement has been modified so that at least one of the mentors has current NIEHS funding. The requirement that trainees sign a statement of intent to pursue environmental health science training has been deleted. Details have been provided on how the trainees will be assigned to mentors. The time that trainees will spend in research in their initial years has been clarified and justified. There has been clarification given about how mentors can been changed as a trainee's research topic is chosen. An evaluation form has been provided for assessing a trainee's presentation skills. Dr. Weir's role as Associate Director has been re-structured. The tracking system of alumni of the program has been modified to capture environmental health science activities. Explanation has been provided about the use of T32 support for the first 3 years of training. The role of the dual mentors on the same research project has been clarified. The proposed number of trainees to be supported has been reduced to 4 pre-doctoral and 2 postdoctoral in the initial year, ramping up to 8 pre-doctoral and 4 postdoctoral by year 5.

描述（由申请人提供） 华盛顿大学生物统计学系与计算机科学，流行病学，基因组科学，医学，病理学，环境和职业健康科学的教师合作，统计学提议培训生物统计学家和生命科学家，以开发和将定量方法应用于环境健康方案“新的环境科学和Bio new Iniborical Insemantialfiolationf”科学。”拟议的培训计划有两种途径：一个基于人群的和一个基于实验室的途径。基于人群的途径将强调环境流行病学中的统计方法，以阐明与环境相关疾病的病因。 基于实验室的途径将集中于现代基因组数据的解释，以及如何利用它们来揭示这些疾病的生物学基础。 这两种途径都将培养一个多学科，协作和跨学科的培训环境，其中1）包括定量和应用培训目标，2）为每个受训者分配一个定量和科学指导者，3）涉及每个受训者，在一个项目中涉及一个项目，导致在多个学科中培训的培训，以增强环境科学研究的培训，以增强环境科学研究的培训，4）招募且招募的背景，4）目标。 调查人员提出了一项学员招聘策略，该策略将从四名博士后和两名博士后学员开始，并在五年级的八名博士后和4名博士后学员。受训人员将从多个学科中招募，每个学科都将在开发定量技能的共同主题中统一的个性化培训计划，以应用于环境健康科学。博士前学员将获得博士学位。生物统计学，环境健康，流行病学或基因组科学学位，而博士后学员有资格在适当的学科中寻求MPH或MS学位。这些受训者将由合作部门的23位教职员工组成的杰出团体，他们都有大量的培训和研究记录。这些主持人将指导学员的研究，并为教学课程教学，并提供有关研究道德和实验室和人口研究管理的培训。 背景 自初次提交以来，该应用程序已经进行了实质性更改。 博士前计划的描述已扩展，以提供有关课程的具体细节。 已经提供了双重指导计划及其导致计划集成的示例。 双重指导安排已被修改，以便至少一位导师拥有当前的NIEHS资金。 删除了学员签署意图进行环境健康科学培训的意图声明的要求。 已经提供了有关如何将学员分配给导师的详细信息。 学员在最初几年中花费的时间已得到澄清和合理。 关于如何选择导师的研究主题，已经澄清了如何更改导师。 已经提供了评估表，用于评估学员的演讲技巧。 威尔博士担任副主任的角色已重新结构。 该计划的校友跟踪系统已被修改以捕获环境健康科学活动。 已经提供了有关在培训前三年使用T32支持的解释。 双重导师在同一研究项目中的作用已澄清。 拟议的受训人员在第一年中已减少到4个博士后和2个博士后，到5年级时最多增加了8个博士后和4个博士后。