Center for Dissemination and Implementation At Stanford (C-DIAS): Research Core

斯坦福大学传播与实施中心 (C-DIAS)：研究核心

• 批准号: 10668470
• 负责人: Lisa Saldana
• 金额: $ 86.98万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10668470
• 关键词: Acceleration; Acute; Address; Adoption; Behavior Therapy; COVID-19; Clinical; Communities; Community Health Systems; Community Practice; Complex; Disparity; Dissemination and Implementation; Effectiveness; Ensure; Epidemic; Equity; Evidence based intervention; Evidence based practice; Funding; Goals; Health Services Research; Healthcare Systems; Improve Access; Individual; Intervention; Investments; Knowledge; Laboratory Research; Learning; Measures; Methodology; Methods; Modeling; Monitor; Motivation; National Institute of Drug Abuse; Outcome; Patients; Persons; Pharmacological Treatment; Policies; Policy Maker; Positioning Attribute; Privatization; Process; Research; Research Methodology; Research Project Grants; Resource-limited setting; Resources; Scientific Advances and Accomplishments; Scientist; Standardization; Substance Use Disorder; System; Techniques; Time; Translating; Underrepresented Populations; United States National Institutes of Health; Variant; Work; access disparities; addiction; community setting; contextual factors; cost; design; disparity gap; effective therapy; effectiveness clinical trial; efficacy clinical trial; ethnic minority; evidence base; flexibility; implementation evaluation; implementation facilitation; implementation measures; implementation process; implementation research; implementation science; implementation strategy; improved; innovation; instrument; marginalized population; member; mortality; multidisciplinary; opioid use disorder; pharmacologic; psychosocial; racial minority; response; routine care; scale up; stimulant use disorder; support tools; tool

C-DIAS RESEARCH CORE: PROJECT SUMMARY/ABSTRACT Improved access to evidence-based pharmacological and psychosocial treatments is urgently needed for persons with substance use disorders. Inequity in access to proven treatments is amplified in low-resourced communities and with organizations serving marginalized and underrepresented populations. The lack of rigor and consistency in methods, measures, design and approach undermines efforts to systematically learn how to implement evidence-based interventions across diverse settings. There is an enormous need for greater precision in how to implement and sustain proven interventions for addiction. Interventions and their delivery platforms are the “what” of an implementation endeavor, whereas implementation strategies are the “how” these interventions are installed and/or maintained. Only 2.4% of NIDA-funded research has examined the “how” of implementation strategies, and among these few, wide methodological variation exists. The Center for Dissemination & Implementation At Stanford (C-DIAS) Research Core integrates three teams of experts, led by top research scientists. The teams align with three domains necessary to advance implementation research in addiction: Methods & Measures, Design & Modeling, and Policy & Financing. Three complementary and innovative C-DIAS Research Projects will serve as open laboratories for Research Core activities. The Core will interact bi-directionally with the Research Projects, positioning each to accumulate and disseminate technical knowledge for the field. These synergistic efforts create an unprecedented opportunity for a deeper and accelerated examination of the mechanisms underlying how implementation strategies work, their contextual determinants, and how to select and deliver them to optimize implementation and clinical outcomes. The three Research Core teams, along with the Research Projects, will translate options about how to implement and at what cost for real-world decision-makers. The Research Core will: PREPARE the addiction research and practice communities with pragmatic and standardized methods and measures of implementation strategies for real-world implementation endeavors (Aim 1); IMPLEMENT rigorous examinations of the components and mechanisms of implementation strategies for effectiveness and cost, using innovative designs and modeling techniques, and creating decision-support tools for policymakers and systems leaders (Aim 2); and, SUSTAIN and scale-up evidence-based addiction treatments by identifying barriers, needed policy and financing strategies, and emerging solutions for ensuring their long-term, high quality and equitable delivery in community settings and health systems (Aim 3). Research Core activities directly address NIDA priorities to “better understand the barriers to successful and sustainable implementation of evidence-based practices and to develop implementation strategies that effectively overcome these barriers.” Not incremental, but instead paradigm shifting, the C-DIAS Research Core will add to the best of existing methodologies, and advance generalizable and practical innovations to improve equitable access to proven addiction treatments.

C-DIAS 研究核心：项目摘要/摘要 迫切需要改善获得循证心理和社会治疗的机会 在资源匮乏的地区，患有药物滥用障碍的人在获得有效治疗方面的不平等现象更加严重。 社区和为边缘化和代表性不足人群服务的组织缺乏严格性。 方法、措施、设计和途径的一致性破坏了系统学习如何 迫切需要在不同环境中实施基于证据的干预措施。 精确地实施和维持经过验证的成瘾干预措施及其实施。 平台是实施工作的“内容”，而实施策略是“如何” 只有 2.4% 的 NIDA 资助的研究进行了这些干预措施的安装和/或维护。 实施策略的“方式”，以及在这些少数策略中，存在广泛的方法差异。 斯坦福大学的传播与实施 (C-DIAS) 研究核心整合了三个专家团队，分别由 这些团队致力于推进实施研究所需的三个领域。 成瘾：方法与措施、设计与建模、政策与融资三者相辅相成。 创新的 C-DIAS 研究项目将作为核心研究活动的开放实验室。 将与研究项目进行双向互动，使每个项目都能够积累和传播 这些协同努力为更深入的研究创造了前所未有的机会。 并加快审查实施战略如何运作的机制、其 背景决定因素，以及如何选择和提供它们以优化实施和临床结果。 三个研究核心团队以及研究项目将翻译有关如何 现实世界决策者的实施和成本是什么 研究核心将： 准备上瘾。 具有务实、规范的实施方法和措施的研究和实践团体 现实世界努力实施的策略（目标 1）； 有效性和成本战略的组成部分和实施机制，利用创新 设计和建模技术，并为政策制定者和系统领导者创建决策支持工具 （目标 2）；以及，通过识别所需的障碍来维持和扩大基于证据的成瘾治疗 政策和融资战略以及确保其长期、高质量和公平的新兴解决方案 社区环境和卫生系统中的交付（目标 3）直接针对 NIDA。 优先事项是“更好地了解成功和可持续实施循证的障碍” 并制定有效实施克服这些障碍的战略。” 但与范式转变相反，C-DIAS 研究核心将补充现有方法的最佳优点，并且 普遍和实用的创新不断进步，以改善获得经过验证的成瘾治疗的公平机会。