SUBCLINICAL ATHEROSCLEROSIS IN HIV INFECTED MEN

HIV 感染男性的亚临床动脉粥样硬化

• 批准号: 7731277
• 负责人: STEVEN K. GRINSPOON
• 金额: $ 10.06万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7731277
• 关键词: Atherosclerosis; Cardiovascular Diseases; Cohort Studies; Computer Retrieval of Information on Scientific Projects Database; Coronary Arteriosclerosis; Funding; Genetic; Grant; HIV; Inflammatory; Institution; Metabolic; Patients; Prevalence; Research; Research Design; Research Personnel; Resources; Source; United States National Institutes of Health; men

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We propose to investigate the prevalence of subclinical coronary atherosclerosis in young HIV-infected patients without previously known cardiovascular disease. We also propose to study the potential metabolic, inflammatory, and genetic factors that may be associated with atherosclerosis in HIV-infected patients. The study design is an observational cross-sectional cohort study to examine the prevalence of early atherosclerotic coronary artery disease using MSCT in 100 HIV infected men as compared to 50 normal healthy control men.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 我们建议研究未经先前已知的心血管疾病的年轻HIV感染患者中亚临床冠状动脉粥样硬化的患病率。 我们还建议研究可能与HIV感染患者的动脉粥样硬化有关的潜在代谢，炎症和遗传因素。 该研究设计是一项观察性横断面研究，旨在检查早期动脉粥样硬化冠状动脉疾病的患病率，其中100名HIV感染的男性与50名正常健康对照男性相比。