Center for End-of-Life Transition Research (CEoLTR)

临终过渡研究中心 (CEoLTR)

• 批准号: 7504044
• 负责人: DIANA J WILKIE
• 金额: $ 46.81万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-29 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7504044
• 关键词: Center; End; Life; Transition; Research

DESCRIPTION (provided by applicant): The overall purpose of the Center for End-of-Life Transition Research is to advance the science of care for people facing the end-of-life transition across the life span (e.g., babies born dying, children, adults, and older adults). We will emphasize patient-centered, family-focused respectful death with planning for end-of life care that is consistent with the patients' and families' values and priorities (e.g., awareness about ways people die and advance care planning) and expected death experiences (e.g., palliative care, approaching dying, and bereavement). The specific aims of this Center application are to: (1) advance nursing science related to the end-of-life transition; (2) strengthen the ethical use of qualitative and quantitative (mixed methods) methodologies by Center investigators/affiliates and train novices regarding the ethical issues in end of life research and mixed methods measurement of biobehavioral (biological, behavioral, and experiential) variables, management of data, and analysis of data; (3) expand the capacity to conduct end of-life research with informatics solutions that contribute to high integrity processes and efficient, valid, and reliable outcomes in institutional and community-based settings; and (4) facilitate the dissemination of end of-life research findings to the scientific and clinical communities and to the general public. Through the Center activities, we will advance the science of disparities in care at end-of-Iife and support research training in this area by providing core services and resources to investigators. The scientific focus is conceptually organized according to an ecologically based, health-related quality of life framework that addresses both person and environmental factors as they interact to affect respectful death outcomes for individuals and families. Studies supported by the Center will be designed to: (a) elucidate underlying physiological, experiential, and behavioral mechanisms that prognosticate or influence approaching death or bereavement; and (b) test culturally relevant interventions for death awareness and respectful death. The research supported by the Center will have a biobehavioral orientation and will include end-of life-care concepts that are measured physiologically (biologic function), experientially (symptoms, perceived health, quality of life), and behaviorally (functional status). The interaction of investigators with expertise in diverse groups of subjects will move the science of end-of-life care forward in new directions. CENTER AS A WHOLE, INCLUDING ADMINISTRATIVE CORE AND EVALUATION PLAN

描述（由申请人提供）：临终过渡研究中心的总体目标是推进对生命周期中面临临终过渡的人们（例如，出生时垂死的婴儿、儿童、成人和老年人）。我们将强调以患者为中心、以家庭为中心的尊重死亡，并根据患者和家属的价值观和优先事项（例如，了解人们死亡方式和提前护理计划）以及预期的死亡经历来规划临终关怀（例如，姑息治疗、濒临死亡和丧亲之痛）。该中心申请的具体目标是：（1）推进与临终过渡相关的护理科学； (2) 加强中心研究者/附属机构对定性和定量（混合方法）方法的道德使用，并培训新手关于临终研究中的道德问题以及生物行为（生物、行为和经验）变量的混合方法测量、管理数据和数据分析； (3) 利用信息学解决方案扩大进行临终研究的能力，这些解决方案有助于在机构和社区环境中实现高度诚信的流程和高效、有效和可靠的结果； (4) 促进向科学和临床界以及公众传播临终研究成果。通过该中心的活动，我们将推进临终护理差异的科学，并通过向研究人员提供核心服务和资源来支持该领域的研究培训。科学重点在概念上根据基于生态的、与健康相关的生活质量框架进行组织，该框架解决了人和环境因素相互作用，影响个人和家庭尊重的死亡结果。该中心支持的研究旨在： (a) 阐明预测或影响临近死亡或丧亲之痛的潜在生理、经验和行为机制； (b) 测试与文化相关的死亡意识和尊重死亡的干预措施。该中心支持的研究将以生物行为为导向，包括从生理（生物功能）、经验（症状、感知健康、生活质量）和行为（功能状态）角度测量的临终关怀概念。研究人员与不同学科群体的专业知识的互动将推动临终关怀科学向新的方向发展。 中心整体，包括管理核心和评估计划