Use of Digital Phenotyping to Understand Digital Media Influence on Adolescent Substance Use

使用数字表型来了解数字媒体对青少年药物使用的影响

• 批准号: 10661933
• 负责人: Meredith Gansner
• 金额: $ 19.31万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10661933
• 关键词: 18 year old; Address; Adolescent; Advertisements; Age; Alcohol consumption; Alcohols; Anxiety; Behavioral; Categories; Cellular Phone; Clinical; Communication; Communities; Complex; Cross-Sectional Studies; Data; Distress; Drug Experimentation; Drug Prescriptions; Drug usage; Emotions; Environmental Risk Factor; Epidemiology; Exposure to; Gender; Goals; Heterogeneity; Individual; Internet; Intervention; Language; Link; Longevity; Longitudinal Studies; Mental Depression; Methodology; Mission; National Institute of Drug Abuse; Outcome; Participant; Pathway interactions; Personal Communication; Pharmaceutical Preparations; Phenotype; Prevention strategy; Protocols documentation; Psychosocial Factor; Questionnaires; Recording of previous events; Reporting; Research; Research Personnel; Risk; Role; Sampling; Secondary to; Self Disclosure; Statistical Methods; Substance Use Disorder; Survey Methodology; Surveys; Technology; Teenagers; Time; Training; Training Programs; Victimization; Visualization; Youth; adolescent alcohol and drug use; adolescent drug use; adolescent substance use; aged; cyberbullying; design; digital; digital media; digital platform; emerging adult; ethnic minority; experience; high risk; high-risk adolescents; improved; longitudinal analysis; minority children; mortality; novel; overdose death; peer; psychiatric symptom; psychosocial; racial minority; racism; sensor; smartphone application; social; social factors; social media; substance use; tool; treatment planning

Project Summary This candidate is requesting support for a four-year program of training and research to use digital phenotyping to gain a novel understanding of how digital media influences like exposure to drug and alcohol- related content online can impact adolescent substance procurement and use. Addressing adolescent substance use is challenging due to the diverse social and environmental factors that can impact a youth’s decision to experiment with drugs or alcohol. Digital media use, including online exposure to substance-related content, is one such potential factor of growing daily influence in adolescent lives. However, little is currently known about how exposure to drug and alcohol-related content differs across media platforms (e.g. gaming, social media), nor whether exposure on one media platform may be more likely to facilitate drug procurement or precipitate an instance of substance use. This limitation in our understanding of these relationships is secondary to both recall bias and the cross-sectional survey methodology used in prior studies. This project will leverage novel digital phenotyping (DP) technology to collect smartphone sensor data in combination with active surveys about digital media exposures and substance use. In this manner, we plan to identify more accurately those digital media exposures and experiences that impact adolescent use of drugs and alcohol, and improve upon existing clinical guidance accordingly. In the proposed training plan, the candidate will build upon her previous experience in use of digital phenotyping to understand high-risk adolescent digital media use. Her training plan includes training in: 1) statistical methods for multivariate longitudinal analysis, 2) design and implementation of digital phenotyping tools that capture high-risk digital experiences/exposures in real time, 3) design and piloting of ecological momentary intervention protocols, and 4) responsible conduct of digital phenotyping research in adolescents with a history of substance use. In line with NIDA’s mission of identifying behavioral, environmental and social causes of substance use across the lifespan, this research plan will 1) determine which subtypes of digital media use are more frequently associated with exposure to drug and alcohol-related content and 2) assess which exposures are more frequently associated with instances of substance procurement and use. We will also explore the potential moderating effects of psychiatric symptoms and online victimization on the relationship between exposure to substance-related content and substance use. This study will be performed across 2 years in subjects between 15 and 18 years of age. A subsequent R01 proposal will then outline the design and pilot of an ecological momentary intervention protocol with the goal of intervening in real time upon digital exposures/experiences associated with adolescent substance use.

项目概要 该候选人请求支持一项为期四年的培训和研究计划，以使用数字技术 表型分析以获得对数字媒体如何影响（例如接触毒品和酒精）的新理解 在线相关内容可能会影响青少年物质的购买和使用。 由于多种社会和环境因素会影响青少年的物质使用，因此物质使用具有挑战性 决定尝试使用酒精或药物，包括在线接触与物质相关的内容。 内容，是对青少年生活产生日益增长的影响的潜在因素之一，但目前还很少。 了解不同媒体平台（例如游戏、 社交媒体），也不是在一个媒体平台上的曝光是否更有可能促进药品采购 我们对这些关系的理解存在局限性。 次要的是回忆偏差和先前研究中使用的横断面调查方法。 将利用新颖的数字表型（DP）技术来收集智能手机传感器数据 关于数字媒体曝光和物质使用的积极调查，我们计划确定更多。 准确地影响青少年吸毒和酗酒的数字媒体曝光和体验， 并相应地改进现有的临床指导 在拟议的培训计划中，候选人将建立。 根据她之前使用数字表型分析来了解高风险青少年数字媒体的经验 她的培训计划包括以下方面的培训：1) 多元纵向分析的统计方法，2) 设计。 以及实施数字表型分析工具，以真实捕获高风险的数字体验/暴露 时间，3) 生态瞬时干预方案的设计和试点，以及 4) 负责任的行为 对有药物使用史的青少年进行数字表型研究。 符合 NIDA 确定物质使用的行为、环境和社会原因的使命 在整个生命周期中，该研究计划将 1) 确定哪些子类型的数字媒体使用更频繁 经常与接触毒品和酒精相关内容相关，并且 2) 评估哪些接触是 我们还将探讨更频繁地与物质采购和使用实例相关的问题。 精神症状和网络受害对两者关系的潜在调节作用 该研究将在 2 年时间内进行。 随后的 R01 提案将概述 15 至 18 岁之间的受试者的设计和试点。 一种生态瞬时干预协议，其目标是对数字化进行实时干预 与青少年物质使用相关的接触/经历。