SNP Confirmation and High Throughput Genotyping Core

SNP 确认和高通量基因分型核心

• 批准号: 7938655
• 负责人: KENNETH M KAUFMAN
• 金额: $ 14.1万
• 依托单位: OKLAHOMA MEDICAL RESEARCH FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7938655
• 关键词: Arts; DNA Sequence; Data; Data Analyses; Data Collection; Development; Education; Equilibrium; Equipment; Genotype; Goals; Human Resources; Individual; Institution; Interdisciplinary Study; Life; Mentors; Methods; Mus; Nucleic Acids; Oklahoma; Quality Control; Research; Research Personnel; Research Project Grants; Rheumatism; Services; Single Nucleotide Polymorphism; Tandem Repeat Sequences; Technology; Training; Work; assay development; deletion analysis; experience; genetic analysis; insertion/deletion mutation; man; meetings; nucleotide metabolism; research study; skills; success

The capabilities assembled in the SNP Confirmation and High Throughput Genotyping Core (SNP-Gen Core) provide the Center Investigators (and larger institution) a single point of entry, comprehensive advice (mentoring) for the technical aspects of experiments manipulating nucleic acids, access to highly-trained technical personnel and very sophisticated and expensive equipment. For most, the Core will offer assay development, data collection, or nucleotide synthesis. In some situations advice and education will be obtained. This Core centralizes the equipment and experience needed to efficiently and reliably produce high quality nucleic acid analysis data. The services available through this Core include DMA sequencing, single nucleotide polymorphism (SNP) genotyping, insertion/deletion analysis, tandem repeat genotyping, expression arrays in mouse and man, and SNP arrays. Appropriate internal quality control checks and balances are in place and are outlined in the revised application. The interaction with each of the Center Investigators will be tailored so that the individual training needs of each are met. The core serves to provide data and services efficiently and economically. In some situations massive high throughput data will be generated.

在SNP确认和高通量基因分型中组装的功能 核心（SNP-GEN核心）为中心调查人员（和较大的机构）提供了一个点 进入，有关实验技术方面的全面建议（指导） 操纵核酸，进入高度训练的技术人员，非常 精致且昂贵的设备。对于大多数人来说，核心将提供测定开发， 数据收集或核苷酸合成。在某些情况下，建议和教育将是 获得。该核心集中了有效和经验的设备和经验 可靠地产生高质量的核酸分析数据。通过此提供的服务 核心包括DMA测序，单核苷酸多态性（SNP）基因分型， 插入/缺失分析，串联重复基因分型，在小鼠和 男人和SNP阵列。适当的内部质量控制检查和平衡已经就位 并在修订的申请中概述。与每个中心的相互作用 调查人员将受到量身定制，以便满足每个人的个人培训需求。核心 有效，经济上提供数据和服务。在某些情况下 将生成大量高通量数据。