Developmental Research Program

发展研究计划

• 批准号: 7510717
• 负责人: GARY L CLAYMAN
• 金额: $ 9.2万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7510717
• 关键词: Area; Award; Budgets; Cancer Center; Carbon; Collaborations; Communities; Data; Dental; Development; Doctor of Medicine; Doctor of Philosophy; Extramural Activities; Fluorescent Dyes; Fostering; Funding; Goals; Grant; Head; Head and Neck Cancer; Image; Incidence; Institutes; Investigation; Lead; Malignant - descriptor; Methods; Minority; Nanotechnology; Neck; Numbers; Oral; Patients; Peer Review; Pilot Projects; Premalignant; Process; Program Research Project Grants; Puerto Rico; Qualifying; Quality of life; Rate; Reproduction spores; Research; Research Personnel; Research Project Grants; Research Proposals; Rice; Texas; Tobacco; Translational Research; Universities; University of Texas M D Anderson Cancer Center; Woman; base; career; craniofacial; falls; improved; innovation; malignant mouth neoplasm; mortality; nanoparticle; novel; oncology; outreach; programs; response; Area; Award; Budgets; Cancer Center; Carbon; Collaborations; Communities; Data; Dental; Development; Doctor of Medicine; Doctor of Philosophy; Extramural Activities; Fluorescent Dyes; Fostering; Funding; Goals; Grant; Head; Head and Neck Cancer; Image; Incidence; Institutes; Investigation; Lead; Malignant - descriptor; Methods; Minority; Nanotechnology; Neck; Numbers; Oral; Patients; Peer Review; Pilot Projects; Premalignant; Process; Program Research Project Grants; Puerto Rico; Qualifying; Quality of life; Rate; Reproduction spores; Research; Research Personnel; Research Project Grants; Research Proposals; Rice; Texas; Tobacco; Translational Research; Universities; University of Texas M D Anderson Cancer Center; Woman; base; career; craniofacial; falls; improved; innovation; malignant mouth neoplasm; mortality; nanoparticle; novel; oncology; outreach; programs; response

A major goal of this SPORE and, more specifically, this program is to identify and fund projects that will lead to clinically testable hypotheses aimed at reducing the incidence and mortality rate of head and neck cancer or improving the quality of life of patients with head and neck cancers. The DRP has continued to support new, novel research in head and neck cancer, with 12 DRP awards made to talented investigators (Mitchell Frederick, Ph.D., Ann Marie Gillenwater, M.D., Michael Story, Ph.D., Ho-Young Lee, Ph.D., Julie Izzo, M.D., Vassiliki A. Papadimitrakopoulou, M.D., Mahitosh Mandel, Ph.D., K.S. Clifford Chao, M.D., Pulivarthi Rao, Ph.D., Gianpietro Dotti, M.D., Nadarajah Vigneswaran, D.M.D., and Waldemar Priebe, Ph.D., over the past 4 years. In addition, 12 DRP proposals were submitted in response to the Fall 2006 solicitation, which were recently reviewed and, with input of our Internal Advisors and Executive Committee, will allow funding of three additional awards to Faye M. Johnson, M.D., Ph.D., Ja Seok Koo, Ph.D., in early 2007, and a subsequent award to an investigator from Rice University, Rebecca Kortum-Richards, Ph.D. The specific objectives of the Developmental Research Program are to: 1. Solicit pilot projects in head and neck cancer translational research that have significant potential for reducing the incidence and mortality rate of head and neck cancer and/or improving the quality of life of patients with head and neck cancers. 2. Foster collaborative efforts among SPORE investigators and with other investigators to encourage the development of new and innovative ideas and approaches. 3. Encourage and assist young investigators with promising preliminary data developed with support of this Program to apply for extramural peer-reviewed funding. 4. When necessary or possible, promote the most promising projects in the Developmental Research Program to full SPORE research projects. The projects funded through the Developmental Research Program are diverse but share common themes related to their translational potential in head and neck cancers. In response to our previous review, we have revised and clarified the process by which applications are solicited from qualified candidates, and have initiated a new collaboration, based on an institutional U54 grant ("Partnership for Excellence"), with the Puerto Rico Cancer Center at the University of Puerto Rico to enhance our outreach in soliciting novel developmental projects from qualified candidates, particularly women and minority investigators. We believe these and other changes to our application will significantly strengthen this program over the next grant cycle.

该孢子的主要目标，更具体地说，该计划是识别和资助将领导的项目 旨在降低头颈癌的发病率和死亡率的临床可检验的假设 或改善头颈癌患者的生活质量。 DRP继续支持 头颈癌的新型新型研究，并为才华横溢的调查人员颁发了12项DRP奖项（Mitchell 弗雷德里克（Frederick）博士，医学博士Ann Marie Gillenwater，Michael Story，Ph.D。 Vassiliki A. Papadimitrakopoulou，医学博士，Mahitosh Mandel，博士，K.S。 Clifford Chao，医学博士，Pulivarthi Rao， 过去4博士，医学博士Gianpietro Dotti，M.D.，Nadarajah Vigneswaran和Priebe博士 年。此外，针对2006年秋季的招标提交了12项DRP建议，这是 最近对内部顾问和执行委员会的意见进行了审查，并将允许资助 M.D. Faye M. Johnson博士，Ja Seok Koo博士，博士，2007年初的三个奖项 随后授予赖斯大学的调查员丽贝卡·科尔图姆·里奇（Rebecca Kortum-Richards）博士学位。具体 发展研究计划的目标是： 1。征求头颈癌转化研究中的飞行员项目，具有巨大潜力 降低头颈癌的发病率和死亡率和/或改善生活质量 头颈癌的患者。 2。在孢子调查人员和其他调查人员之间促进合作努力，以鼓励 开发新的创新思想和方法。 3.鼓励和协助年轻的调查员在支持此处制定有希望的初步数据 申请校外同行评审资金的计划。 4.在必要或可能的情况下，促进发展研究中最有前途的项目 计划完整的孢子研究项目。 通过发展研究计划资助的项目多种多样，但共享共同的主题 与它们在头颈癌中的翻译潜力有关。为了回应我们以前的评论，我们有 修订并阐明了从合格候选人中征求申请的过程，并 基于机构U54赠款（“卓越合作伙伴关系”）的新合作 波多黎各大学的波多黎各癌症中心，以增强我们招募小说的宣传 合格候选人，尤其是妇女和少数派研究人员的发展项目。我们相信 这些应用程序的这些和其他更改将大大加强该计划的下一个赠款 循环。