CORE--TISSUE PROCUREMENT

核心——纸巾采购

• 批准号: 6485994
• 负责人: GARY L CLAYMAN
• 金额: $ 19.62万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-06 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6485994
• 关键词: basal cell carcinoma; basosquamous cell carcinoma; biomedical facility; clinical depression; clone cells; histology; human genetic material tag; human tissue; in situ hybridization; lymphocyte; skin neoplasms; tissue /cell preparation; tissue resource /registry

The Tissue Procurement Core Facility for t his Program Project will provide services to each investigator. This will enhance each project, increase the efficient use of time and funds, and ensure coordination between projects. The Core will obtain human tumor tissue and maintain a bank of frozen malignant tumors, adjacent non-malignant skin, non-sun exposed skin and peripheral blood lymphocytes. It will also maintain laboratory specimen coding to maintain patient confidentiality and prevent experimental bias. Tumor cell line will also be maintained in the Core and distributed amongst investigators as required. All specimens will be histologically verified. Central processing of tumors for mRNA, DNA, and protein will be provided for all projects through the Core facility allowing: 1) a safe, central repository of essential materials for the research project s with accurate coded record keeping capabilities. 2) efficient utilization of scarce materials by multiple investigators. 3) standardization of collection, storage, and processing procedures, ensuring uniformity of materials obtained by different investigators. 4) An efficient tracking, delivery, and processing system that adjusts and meets the tissue requirements for the program project.

其计划项目的组织采购核心设施​​将提供 为每个调查员提供服务。 这将增强每个项目，增加 有效利用时间和资金，并确保 项目。 核心将获得人类肿瘤组织，并保持 冷冻恶性肿瘤，邻近的非恶性皮肤，非裸露的皮肤 和外周血淋巴细胞。 它也将维护实验室 标本编码以维持患者机密性并防止 实验偏见。 肿瘤细胞系也将保持在核心和 根据需要在调查人员之间分发。 所有标本将是 组织学验证。 mRNA，DNA和 将通过核心设施为所有项目提供蛋白质 允许：1）安全的中央存储库 具有准确的编码记录保留功能的研究项目。 2） 多个研究人员对稀缺材料的有效利用。 3） 收集，存储和处理程序的标准化，确保 不同研究者获得的材料的均匀性。 4） 调整和满足的有效跟踪，交付和处理系统 该计划项目的组织要求。