The WashU-UCSC-EBI Human Genome Reference Center."

华盛顿大学-UCSC-EBI 人类基因组参考中心。”

• 批准号: 10419218
• 负责人: Paul Flicek
• 金额: $ 25万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-23 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10419218
• 关键词: Awareness; Biomedical Research; Communication; Communities; Community Health; Data; Education and Outreach; Educational Materials; Ensure; Genome; Genomics; Goals; Health; Human; Individual; International; Maintenance; Medical; Population; Precision Health; Protocols documentation; Secure; Standardization; Update; base; community building; data resource; genetic information; human pangenome; human reference genome; improved; international partnership; outreach program; pan-genome; programs; tool; virtual; website development

PROJECT SUMMARY (PROJECT 2 SUPPLEMENT) The goal of the WashU-UCSC-EBI based Human Genome Reference Center (HGRC) is to maintain and update the new human genome reference produced by the Human Genome Reference Program (HGRP) and to provide it to the scientific community. The goal of the HGRP Outreach and Education Center (HGRP-OE) is to communication with the entire scientific and medical communities and disseminate data, resources, tools, protocols, and educational materials. In this supplement, we plan to significantly expand our outreach and education effort to form a strategic partnership between the Global Alliance for Genomics and Health (GA4GH) and the Human Pangenome Project (including the Human Pangenome Reference Consortium and international partnerships). We will establish, develop and coordinate the Global Pangenome Reference Community to assist in ensuring the (a) organization and communications needs for this community; (b) website development and maintenance; (c) integration with HPRC Coordination Center and GA4GH Community. If successfully implemented, our proposed expansion will greatly increase community awareness of the new human genome reference and its usage, and thus maximize its use, value, and significance; and will expand the use and application of tools to facilitate secure and responsible data-sharing, and further engage global and national projects in genomics and precision health.

项目摘要（项目 2 补充） 基于 WashU-UCSC-EBI 的人类基因组参考中心 (HGRC) 的目标是维护和 更新人类基因组参考计划 (HGRP) 生成的新人类基因组参考，以及 将其提供给科学界。 HGRP 外展和教育中心 (HGRP-OE) 的目标是 与整个科学界和医学界沟通并传播数据、资源、工具、 协议和教育材料。在本增刊中，我们计划大幅扩大我们的服务范围并 全球基因组学与健康联盟 (GA4GH) 之间建立战略伙伴关系的教育努力 和人类泛基因组计划（包括人类泛基因组参考联盟和国际 伙伴关系）。我们将建立、发展和协调全球泛基因组参考社区来协助 确保 (a) 该社区的组织和沟通需求； (b) 网站开发和 维护; (c) 与 HPRC 协调中心和 GA4GH 社区整合。如果成功的话 实施后，我们提出的扩展将大大提高社区对新人类基因组的认识 参考及其使用，从而最大限度地发挥其用途、价值和意义；并将扩大使用范围和 应用工具促进安全和负责任的数据共享，并进一步参与全球和国家 基因组学和精准健康项目。