Small Animal Imaging

小动物成像

• 批准号: 7712919
• 负责人: RICHARD G PESTELL
• 金额: $ 6.17万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-05 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7712919
• 关键词: Advisory Committees; Animal Housing; Animals; Arts; Cancer Center; Custom; Data; Funding; Generations; Guidelines; Image; Imaging Techniques; Internet; Invasive; Investigation; Journals; Laboratory Animals; Magnetic Resonance Imaging; Malignant Neoplasms; Mission; Modality; Mus; Neurologic; Oryctolagus cuniculus; Peer Review; Photons; Physiology; Positron-Emission Tomography; Productivity; Protocols documentation; Publications; Radiology Specialty; Rattus; Research; Research Personnel; Resource Sharing; Resources; Score; Services; Small Animal Imaging Shared Resource; Techniques; Training; Translational Research; Ultrasonography; Universities; Veterinarians; X-Ray Computed Tomography; anticancer research; in vivo; innovation; member; molecular imaging; oncology; optical imaging; pre-clinical; single photon emission computed tomography; tomography

SMALL ANIMAL IMAGING SHARED RESOURCE The Small Animal Imaging Shared Resource provides state-of-the-art in vivo molecular imaging capabilities to the investigators of the Kimmel Cancer Center. It was established under the direction of Dr. Mathew Thakur in April 2004 supported, to date, by the Thomas Jefferson University and the Department of Radiology. This resource provides non-invasive small animal imaging, with PET, SPECT, CT and ultrasound. These modalities offer innovative basic, as well as pre-clinical translational, research capabilities for studying patho-physiology and genesis of cancer. In addition to providing comprehensive imaging services the expertise exists to a) custom synthesize probes specific for targeted bio-markers; b) develop new image generation and analysis techniques; and c) train cancer investigators to harness the strengths of molecular imaging. The facility is supported by three AALAC accredited animal houses and two veterinarian staff members. Thus far this shared resource has supported fifteen federally funded investigations related to oncology and enhanced productivity as depicted by several publications in peer-reviewed journals.

小动物成像共享资源 小型动物成像共享资源提供了最先进的体内分子成像功能 致金梅尔癌症中心的研究人员。它是在马修博士的指导下建立的 塔库尔（Thakur）于2004年4月支持托马斯·杰斐逊大学（Thomas Jefferson University）和系 放射学。该资源可提供非侵入性的小动物成像，并具有PET，SPECT，CT和超声波。 这些方式提供了创新的基本基础以及临床前翻译的研究能力 癌症的病理生理学和起源。除了提供全面的成像服务外 存在专业知识，a）自定义合成探针针对目标生物标志物的特定探针； b）开发新图像 生成和分析技术； c）训练癌症研究者以利用分子的优势 成像。该设施得到了三个AALAC认可的动物房和两名兽医工作人员的支持 成员。到目前为止，该共享资源支持了15项与 肿瘤学和增强的生产力，如经同行评审期刊中的几个出版物所描绘的。