Core Support for Cancer Center

癌症中心的核心支持

基本信息

批准号：
7680627
负责人：
Israel DAVID GOLDMAN
金额：
$ 24.9万
依托单位：
ALBERT EINSTEIN COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-06-01 至 2012-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7680627
关键词：
Advisory Committees Albert Einstein Cancer Center Animals Behavioral Bioinformatics Biology Biostatistics Shared Resource Cancer Center Cancer Center Support Grant Clinical Oncology Colon Carcinoma DNA Sequence Epidemiology Funding Gene Targeting Genetic Genetic Medicine Genetics and Medicine Genome Genomics Grant Histopathology Housing Image Immunooncology Informatics Intestinal Cancer Leadership Malignant Neoplasms Medical Oncology Membrane Biology Molecular Neoplasm Metastasis Numbers Nutritional Pediatric Hematology/Oncology Population Sciences Positioning Attribute Prevention Price Program Research Project Grants Proteomics Radiation Oncology Recruitment Activity Resource Sharing Roentgen Rays Scientist Services Synchrotrons Therapeutic Transgenic Animals Transgenic Organisms cancer epidemiology cell growth cell motility member programs research facility structural biology tumor

项目摘要

DESCRIPTION (provided by applicant): This is an application for renewed CCSG funding for year 35 of the Albert Einstein Cancer Center which received its first NCI designation in 1972. There are seven established programs. These include: Immunooncology (Scharff), Tumor Microenvironment and Metastasis (Condeelis), Cell Growth and Differentiation control (Skoultchi), Molecular Membrane Biology (Stanley), Experimental Therapeutics (Horwitz), Cancer Epidemiology (Rohan) and the Biology of Colon Cancer (Augenlicht). The enhanced cancer focus of AECC programs is reflected in an increase in NCI grants from 74 in 2000 to 95 in 2006 with NCI support to AECC members currently at $19.4M (direct). There are two new NCI-funded programmatic grants: an NCI program project grant on Motility and Invasion and a U54 Center grant on Nutritional-Genetic Interactions in Intestinal Cancer. There has been recruitment of 43 new AECC members of whom 30 are new to Einstein. There have been major recruitments to clinical oncology leadership positions including new chairs of Medical Oncology (Perez-Soler), Pediatric Hematology/Oncology (Gorlick) and Radiation Oncology (Kalnicki). There are now 121 AECC members. The External Scientific Advisory Committee has convened yearly and consists of eleven members. There are nine established shared resources including Proteomics, Structural Biology (X-ray, Synchrotron, NMR), FACS, Analytical Imaging, Histopathology, Transgenic, Animal Barrier, Gene Targeting, and Genomics (DNA sequencing + microarray services). A Biostatistics Shared Resource was funded through a supplement to the CCSG since the last review and is included in this application. New shared resources for which funding is requested include Bioinformatics, Genome Imaging (FISH/SKY), and Epidemiology Informatics. A new research facility, the Michael F. Price Center for Translational and Genetic Medicine will open December 2007 and will provide 20,000 ft2 for the Animal Barrier, Transgenic, Histopathology, and Gene Targeting Shared Resources. A substantial number of new AECC recruits will be housed in this facility. Beyond this, there are plans to expand population sciences through continued recruitment to the Cancer Epidemiology program and recruitment of behavioral/prevention scientists.

描述（由申请人提供）：这是为阿尔伯特·爱因斯坦癌症中心（Albert Einstein Cancer Center）第35年更新CCSG资金的申请，该中心于1972年获得了NCI的第一个名称。有七个既定计划。其中包括：免疫学（Scharff），肿瘤微环境和转移（Condeelis），细胞生长和分化控制（Skoultchi），分子膜生物学（Stanley），实验性疗法（HORWITZ），HORWITZ），癌症癌症流行病学（Rohan）（Rohan）和结肠癌的生物学（Augenerlichlichlicht）。 AECC计划的癌症焦点增强反映在NCI赠款从2000年的74助理增加到2006年的95个，而NCI为AECC成员的支持目前为1940万美元（直接）。 NCI资助的计划赠款有两个新的：NCI计划项目赠款有关运动和入侵的赠款，以及肠癌中营养基因相互作用的U54中心拨款。已经招募了43位新的AECC成员，其中30名是爱因斯坦的新成员。临床肿瘤学领导职位已有重大招募，包括新的医学肿瘤学主持（Perez-Soler），儿科血液学/肿瘤学（Gorlick）和放射肿瘤学（Kalnicki）。现在有121名AECC成员。外部科学咨询委员会每年召集，由11名成员组成。有九种已建立的共享资源，包括蛋白质组学，结构生物学（X射线，同步加速器，NMR），FACS，分析成像，组织病理学，转基因，动物屏障，基因靶向和基因组学（DNA测序 +微阵列服务）。自上次审查以来，通过对CCSG的补充来资助生物统计学共享资源，并包括在本申请中。要求资金的新共享资源包括生物信息学，基因组成像（鱼/天空）和流行病学信息学。 Michael F. Price Center for Translational and Genetic Medicine是一个新的研究机构，将于2007年12月开放，并将为动物屏障，转基因，组织病理学和基因靶向共享资源提供20,000 FT2。该设施将容纳大量新的AECC新兵。除此之外，还有计划通过继续招募癌症流行病学计划和行为/预防科学家的招募来扩大人口科学。