CORE GRANT FOR VISION RESEARCH

愿景研究核心资助

• 批准号: 7616137
• 负责人: Dianna Ammons Johnson
• 金额: $ 38.27万
• 依托单位: UNIVERSITY OF TENNESSEE HEALTH SCI CTR
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-04-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7616137
• 关键词: CORE; GRANT; VISION; RESEARCH

DESCRIPTION (provided by applicant): For the past four years, the University of Tennessee (UT) Memphis Core Grant for Vision Research has provided support that has been critical for accomplishing our major programmatic goals of 1) building of the new Hamilton Eye Institute to provide 15,000 square feet of new research laboratories and core facilities, plus plans for an additional 15,000 square feet in Phase III of the construction; 2) recruitment of seven exceptional Ph.D or M.D./Ph.D vision research faculty; 3) building strong research and training collaborations with St. Jude Children's Research Hospital and with a number of UT research centers. The accomplishments of individual Core participants have equally impressive. Since our last Core Grant submission, the 22 participants utilizing Core facilities have produced over 335 publications. Plans for the next funding period include strengthening the two existing Core Modules. The Imaging Module consists of three high-resolution digital image analysis systems for light microscopy, a rapid-response calcium imaging system and technical assistance for microscopy procedures. Funds for a new confocal microscope and cryostat are requested. The Molecular Biology Module provides automated DNA sequencing and genotyping, quantitative real-time PCR, and gene array chip scanning technology. Major pieces of new equipment to be purchased with Core Grant funds for this module include a Typhoon Workstation Imager, UV 96 well plate reader, and ultracentrifuge. Additional vision research faculty will be recruited to fill the newly created space in the Hamilton Eye Institute. Collaborations between St. Jude Children's Research Hospital and UT will grow with the expected award of large interdisciplinary grants involving investigators from both institutions. The administration of both institutions strongly supports the continued growth of vision research.

描述（由申请人提供）：在过去的四年中，田纳西大学（UT）孟菲斯核心研究提供了支持，这提供了支持，这对于实现我们的重大程序化目标至关重要。 2）招募七个杰出博士学位或M.D./PH.D Vision Research Faculty； 3）与圣裘德儿童研究医院以及许多UT研究中心建立强大的研究和培训合作。个别核心参与者的成就同样令人印象深刻。自从我们上次核心赠款提交以来，利用核心设施的22名参与者已经制作了335多个出版物。下一个资金期限的计划包括加强两个现有的核心模块。成像模块由三个高分辨率数字图像分析系统组成，用于光学显微镜，快速响应钙成像系统以及显微镜程序的技术援助。请求新的共聚焦显微镜和低温恒温器的资金。分子生物学模块提供自动的DNA测序和基因分型，定量实时PCR和基因阵列芯片扫描技术。该模块的核心赠款资金将购买的新设备的主要部分包括台风工作站成像仪，UV 96 Well Plate读取器和Ultracentrifuge。将招募其他视觉研究教师，以填补汉密尔顿眼科研究所的新创建的空间。圣裘德儿童研究医院与UT之间的合作将获得预期的大型跨学科赠款，涉及两家机构的调查人员。这两个机构的管理都强烈支持视力研究的持续增长。