CORE GRANT FOR VISION RESEARCH

愿景研究核心资助

• 批准号: 7616137
• 负责人: Dianna Ammons Johnson
• 金额: $ 38.27万
• 依托单位: UNIVERSITY OF TENNESSEE HEALTH SCI CTR
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-04-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7616137
• 关键词: CORE; GRANT; VISION; RESEARCH

DESCRIPTION (provided by applicant): For the past four years, the University of Tennessee (UT) Memphis Core Grant for Vision Research has provided support that has been critical for accomplishing our major programmatic goals of 1) building of the new Hamilton Eye Institute to provide 15,000 square feet of new research laboratories and core facilities, plus plans for an additional 15,000 square feet in Phase III of the construction; 2) recruitment of seven exceptional Ph.D or M.D./Ph.D vision research faculty; 3) building strong research and training collaborations with St. Jude Children's Research Hospital and with a number of UT research centers. The accomplishments of individual Core participants have equally impressive. Since our last Core Grant submission, the 22 participants utilizing Core facilities have produced over 335 publications. Plans for the next funding period include strengthening the two existing Core Modules. The Imaging Module consists of three high-resolution digital image analysis systems for light microscopy, a rapid-response calcium imaging system and technical assistance for microscopy procedures. Funds for a new confocal microscope and cryostat are requested. The Molecular Biology Module provides automated DNA sequencing and genotyping, quantitative real-time PCR, and gene array chip scanning technology. Major pieces of new equipment to be purchased with Core Grant funds for this module include a Typhoon Workstation Imager, UV 96 well plate reader, and ultracentrifuge. Additional vision research faculty will be recruited to fill the newly created space in the Hamilton Eye Institute. Collaborations between St. Jude Children's Research Hospital and UT will grow with the expected award of large interdisciplinary grants involving investigators from both institutions. The administration of both institutions strongly supports the continued growth of vision research.

描述（由申请人提供）：在过去的四年中，田纳西大学 (UT) 孟菲斯视觉研究核心拨款提供的支持对于实现我们的主要计划目标至关重要：1) 建设新的汉密尔顿眼科研究所提供 15,000 平方英尺的新研究实验室和核心设施，并计划在第三阶段建设中额外增加 15,000 平方英尺； 2) 招募七名杰出的博士或医学博士/博士视觉研究人员； 3) 与圣裘德儿童研究医院和一些德克萨斯大学研究中心建立强有力的研究和培训合作。个别核心参与者的成就同样令人印象深刻。自从我们上次提交核心资助以来，利用核心设施的 22 名参与者已经出版了超过 335 篇出版物。下一个资助期的计划包括加强现有的两个核心模块。成像模块由三个用于光学显微镜的高分辨率数字图像分析系统、一个快速响应钙成像系统和显微镜程序的技术援助组成。需要资金购买新的共焦显微镜和低温恒温器。分子生物学模块提供自动化DNA测序和基因分型、定量实时PCR和基因阵列芯片扫描技术。该模块将使用核心拨款资金购买的主要新设备包括 Typhoon 工作站成像仪、UV 96 孔板读取器和超速离心机。将招募更多的视觉研究人员来填补汉密尔顿眼科研究所新创建的空间。圣裘德儿童研究医院和德克萨斯大学之间的合作将随着来自两个机构的研究人员的大规模跨学科资助的预期而不断增长。两个机构的管理都大力支持视觉研究的持续发展。