Emory Alzheimer's Disease Research Center

埃默里阿尔茨海默病研究中心

• 批准号: 10212236
• 负责人: Monica Willis Parker
• 金额: $ 30.84万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10212236
• 关键词: Affect; African American; Alzheimer' s Disease; Alzheimer' s disease related dementia; Alzheimer’s disease biomarker; Basic Science; Brain; Caregiver Burden; Caring; Caucasians; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Clinical; Clinical Research; Clinical Trials; Collaborations; Collection; Communities; Continuing Education; Data; Dementia; Disease; Education and Outreach; Enrollment; Faculty; Family; Fostering; Foundations; Goals; Health; Healthcare; Healthcare Activity; Healthcare Systems; Impaired cognition; Individual; Justice; Knowledge; Latino; Leadership; Lesbian Gay Bisexual Transgender Queer; Magnetic Resonance Imaging; Maintenance; Minority; Minority Groups; Modeling; Nurses; Participant; Persons; Population Heterogeneity; Prevention strategy; Race; Recruitment Activity; Registries; Research; Research Personnel; Research Project Grants; Risk; Services; System; Translational Research; Trust; Underrepresented Minority; Underrepresented Populations; Universities; Vascular Diseases; Visit; Work; base; cohort; community organizations; community partnership; design; ethnic minority population; healthy aging; improved; innovation; member; men; outreach; outreach program; programs; racial difference; racial diversity; recruit; retention rate; social; success

SUMMARY/ABSTRACT: MINORITY ENGAGEMENT CORE The Minority Engagement Core (MEC) focuses on the recruitment and retention of African American (AA) individuals into ADRC research, clinical trials and brain donation programs. The MEC seeks to decrease the knowledge gap about Alzheimer’s Disease (AD) among AA, while increasing participation in basic, clinical, and translational research that also acknowledges and explores racial differences. We will follow a community based participatory model to design and implement programs of mutual benefit to the ADRC and Underrepresented Groups (URG). The Registry for Remembrance (RfR) Community Coalition, established in 2008, consists of lay and professional groups serving the AA community. The RfR and the MEC work together to implement recruitment/retention strategies. The MEC augments but does not duplicate the ongoing recruitment activities of the Administrative, Clinical, and ORE Cores, but rather responds to programming and community requests and needs specific to the AA community. This intentional and directed focus produces trusted relationships that bolster our recruitment to double the number of African-American participants in our UDS cohort and other clinical research efforts. The MEC, in collaboration with the Administrative, Clinical, ORE and Data Cores, will facilitate the recruitment and retention of AA in ADRC studies, and tailor specific outreach to engage AA men and other URG (e.g. Latino and LGBTQ). To increase the understanding of Alzheimer’s disease and related dementias by URG healthcare and other allied professionals, we will provide continuing education opportunities to improve their capacity for service to those living and dealing with these devastating disorders. Our goal of increased URG research participation will be accomplished through the following aims: Aim 1. Increase the participation of persons from the African-American community in clinical trials and other research at the ADRC. Aim 2. Continue outreach, recruitment, and engagement activities centered on capacity-building strategies. Aim 3. Develop and evaluate innovative research, recruitment, and engagement activities aimed at enhancing the relevance of ADRC research for other ethnic minority and underrepresented groups.

摘要/摘要：少数族裔参与核心 少数族裔参与核心 (MEC) 重点关注非裔美国人 (AA) 的招募和保留 MEC 致力于减少个人参与 ADRC 研究、临床试验和大脑捐赠项目。 AA 之间关于阿尔茨海默病 (AD) 的知识差距，同时增加基础、临床和 承认并探索种族差异的转化研究我们将关注一个社区。 基于参与模式来设计和实施对 ADRC 和 代表性不足的群体 (URG)。 纪念登记处 (RfR) 社区联盟，成立于 2008 年，由为 AA 社区服务的外行和专业团体组成，RfR 和 MEC 共同合作。 实施招聘/保留策略 MEC 增强但不重复正在进行的策略。 行政、临床和 ORE 核心的招聘活动，而是响应规划和 AA 社区特有的社区要求和需求产生了这种有意和有针对性的关注。 值得信赖的关系，有助于我们的招募，使我们的非裔美国人参与者数量增加一倍 MEC 与行政、临床、ORE 合作开展 UDS 队列和其他临床研究工作。 和数据核心，将促进 ADRC 研究中 AA 的招募和保留，并定制具体的外展活动 让 AA 男性和其他 URG（例如拉丁裔和 LGBTQ）参与进来，以增进对阿尔茨海默病的了解。 由 URG 医疗保健和其他相关专业人员治疗的疾病和相关痴呆症，我们将提供持续的服务 教育机会，以提高他们为生活和应对这些灾难性事件的人们提供服务的能力 我们增加 URG 研究参与的目标将通过以下目标来实现： 目标 1. 增加非裔美国人社区人士对临床试验和其他活动的参与 ADRC 的研究。 目标 2. 继续以能力建设战略为中心的外展、招聘和参与活动。 目标 3. 开发和评估创新研究、招募和参与活动，旨在增强 ADRC 研究与其他少数民族和代表性不足群体的相关性。