Predoctoral Training Program in Biotechnology

生物技术博士前培训计划

基本信息

批准号：
10200820
负责人：
Robert John Kerns
金额：
$ 21.3万
依托单位：
UNIVERSITY OF IOWA
依托单位国家：
美国
项目类别：
财政年份：
1990
资助国家：
美国
起止时间：
1990-07-01 至 2023-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10200820
关键词：
Biotechnology Training Programs pre-doctoral

项目摘要

Project Summary This application requests continued support for 6 trainees for a Predoctoral Training Program (TP) in Biotechnology that was first funded in 1990. If granted, these 6 lines will be matched by 6 more lines by the University of Iowa, through its Center for Biocatalysis and Bioprocessing (CBB). The CBB will also continue to provide the administrative and additional financial. This institutional match will allow the TP to select a yearly cohort of 12 predoctoral students. The CBB will also provide administrative assistance and training in industrial settings and will expose trainees to commercial aspects of biotechnology. This matching support will greatly increases the effectiveness of the funds requested from NIH and assures an extensive industrial emphasis in training. The TP is designed to provide a deep and diverse education to trainees, including academic training covering qualitative and quantitative aspects of biotechnology, hands- on introduction to industrial methods, and preparation for professional life in biotechnology. Trainees are required to: a) complete an industrial internship for three months; b) take at least one course in each of the three core areas of biotechnology (Biocatalysis, Bioreactors & Bioseparations, Molecular Biology & Genetics); c) take the program's capstone course, “Introduction to Biocatalysis”; d) take a course in Responsible Conduct of Research; e) participate in the “Perspectives in Biocatalysis” class and activities every semester; f) participate in TP's Seminars; g) present research in an annual Biocatalysis and Bioprocessing Conference and the annual TP symposium; and h) participate in various trainee-cohort social and networking activities. Candidates are selected toward the end of their first year in graduate school, and support for trainees may be renewed for up to two years, however all trainees continue in the program until graduation. The recruiting pool is based not on departmental affiliation but on interest in biotechnology, graduate training. Currently 33 trainers from four different colleges, and two interdisciplinary PhD programs participate in this TP. The diverse trainers cohort, together with the CBB partnership, provides trainees with a broad training experience including significant exposure to non-academic career paths. The TP is administered by a Leadership Team (a PI and three Co-PIs) and an Executive Committee. An External Review Panel provides independent input to assure relevance to the leadership and training needs of Biotech industry and research.

项目概要此申请要求继续支持 6 名博士前培训学员生物技术计划 (TP) 于 1990 年首次资助。如果获得批准，这 6 个品系将爱荷华大学通过其生物催化中心匹配另外 6 个系列生物加工 (CBB) 还将继续提供行政和管理服务。这种机构匹配将使 TP 能够每年选择一批人。 CBB 还将提供 12 名博士前学生的行政协助和帮助。工业环境中的培训，将使受训者接触到商业方面的知识这种匹配的支持将大大提高生物技术的有效性。向 NIH 申请资金，并确保工业界广泛重视培训。 TP 旨在为学员提供深入且多样化的教育，包括学术培训涵盖生物技术的定性和定量方面，动手实践介绍工业方法以及为职业生涯做好准备生物技术培训生必须： a) 完成三人的工业实习。 b) 至少学习生物技术三个核心领域的一门课程；（生物催化、生物反应器和生物分离、分子生物学和遗传学）；项目的顶点课程，“生物催化概论” d) 选修以下课程；负责任的研究行为； e) 参与“生物催化展望” 每学期的课程和活动； f) 参加 TP 的研讨会 g) 展示研究成果；参加年度生物催化和生物加工会议以及年度 TP 研讨会； h) 参加各种受训者社交和网络活动。候选人在研究生院第一年结束时被选拔，并且对受训人员的支持最多可以延长两年，但所有受训人员都将继续在该计划中直到毕业。隶属关系但对生物技术感兴趣，目前有 33 名培训师。四所不同的学院和两个跨学科博士项目参与了该 TP。多元化的培训师群体与 CBB 合作伙伴关系为学员提供了广泛的培训经验，包括大量接触非学术职业道路。 TP 由领导团队（一名 PI 和三名 Co-PI）和一名执行人员管理外部审查小组提供独立意见以确保相关性。满足生物技术行业和研究的领导和培训需求。

项目成果

期刊论文数量（163）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Detection, purification, and structural elucidation of the acylhomoserine lactone inducer of Vibrio fischeri luminescence and other related molecules.

费氏弧菌发光的酰基高丝氨酸内酯诱导剂及其他相关分子的检测、纯化和结构阐明。

DOI：
10.1016/s0076-6879(00)05495-1
发表时间：
2024-09-14
期刊：
Methods in enzymology
影响因子：
0
作者：
Amy L. Schaefer;B. Hanzelka;M. Parsek;E. Greenberg
通讯作者：
E. Greenberg

Decrypting a Cryptic Allosteric Pocket in H. pylori Glutamate Racemase.

解密幽门螺杆菌谷氨酸消旋酶中的隐秘变构袋。

DOI：
发表时间：
2021
期刊：
影响因子：
5.9
作者：
Chheda, Pratik Rajesh;Cooling, Grant T;Dean, Sondra F;Propp, Jonah;Hobbs, Kathryn F;Spies, M Ashley
通讯作者：
Spies, M Ashley

Desaturation and oxygenation of 1,2-dihydronaphthalene by toluene and naphthalene dioxygenase.

甲苯和萘双加氧酶对 1,2-二氢萘进行去饱和和氧化。

DOI：
发表时间：
1995-10
期刊：
影响因子：
3.2
作者：
Torok, D S;Resnick, S M;Brand, J M;Cruden, D L;Gibson, D T
通讯作者：
Gibson, D T

Stereospecific oxidation of (R)- and (S)-1-indanol by naphthalene dioxygenase from Pseudomonas sp. strain NCIB 9816-4.

假单胞菌萘双加氧酶对 (R)- 和 (S)-1-茚满醇进行立体定向氧化。

DOI：
发表时间：
1997-05
期刊：
影响因子：
4.4
作者：
Lee, K;Resnick, S M;Gibson, D T
通讯作者：
Gibson, D T

The C7-aminomethylpyrrolidine group rescues the activity of a thio-fluoroquinolone.

C7-氨基甲基吡咯烷基团挽救了硫代氟喹诺酮的活性。

DOI：
发表时间：
2019-05
期刊：
影响因子：
3.9
作者：
Lentz, Sarah R C;Chheda, Pratik R;Oppegard, Lisa M;Towle, Tyrell R;Kerns, Robert J;Hiasa, Hiroshi
通讯作者：
Hiasa, Hiroshi