IDENTIFICATION/CHARACTERIZATION OF VIRUS-INDUCED CELL DEATH GENES IN NICOTIANA

烟草中病毒诱导的细胞死亡基因的鉴定/表征

• 批准号: 7610333
• 负责人: Anthony Cole
• 金额: $ 8.63万
• 依托单位: UNIVERSITY OF SOUTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7610333
• 关键词: Area; Biotechnology; Cell Death; Characteristics; Computer Retrieval of Information on Scientific Projects Database; Development; Funding; Genes; Grant; Institution; Molecular; Molecular Biology; Nicotiana; Pathology; Plant Genes; Plant Viruses; Plants; Proteins; Range; Research; Research Personnel; Resources; Source; Students; Symptoms; System; Tobacco; Tobacco Mosaic Virus; United States National Institutes of Health; Viral; Virus; insight; pathogen; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The characteristic symptoms induced by a plant virus on its host result from the interactions between viral and host gene products. While it has been proven to be relatively easy to identify plant virus genes responsible for symptom development or for host range determination, the mechanisms by which these gene products elicit specific responses or influence host range remain to be fully understood. My research attempts to characterize the viral and plant genes responsible for the hypersensitive response elicited in Nicotiana gossei by Tobacco mosaic virus and the systemic cell death induced in Nicotiana excelsior by Tobacco rattle virus. The information gained from these host-pathogen systems will provide a greater understanding of how these viruses elicit different cell death responses and new insights into the mechanisms of plant virus-induced symptoms. Furthermore, this project exposes undergraduate students to the areas of molecular biology, molecular plant pathology, and the beneficial uses of biotechnology in plant protection.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 植物病毒引起的特征性症状是由于病毒和宿主基因产物之间的相互作用而导致的。尽管事实证明，它相对容易识别负责症状发育或宿主范围测定的植物病毒基因，但这些基因产物引起特定反应或影响宿主范围的机制仍有待完全了解。我的研究试图表征烟草病毒引起的尼古蒂亚纳·戈西（Nicotiana Gossei）引起的过度敏感反应的病毒和植物基因，以及烟草病毒在烟草中诱导的全身细胞死亡。 从这些宿主病原体系统中获得的信息将对这些病毒如何引起不同细胞死亡反应以及对植物病毒诱发症状机制的新见解的更多了解。此外，该项目将本科生暴露于分子生物学，分子植物病理学以及生物技术在植物保护中的有益用途。