Core-003

核心003

• 批准号: 10198072
• 负责人: David H Ellison
• 金额: $ 93.68万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-02 至 2022-08-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10198072
• 关键词: Award; Bioinformatics; Biometry; Clinical; Clinical Competence; Clinical Research; Communities; Competence; Doctor of Pharmacy; Doctor of Philosophy; Evaluation; Experimental Models; Faculty; Funding; Funding Mechanisms; Grant; Human; Intervention; Investigation; Investments; Mentored Clinical Scientist Development Award (K08); Mentors; Mentorship; Methods; NCI Scholars Program; Oregon; Pathway interactions; Physicians; Pilot Projects; Problem Solving; Process; Program Development; Randomized; Research; Research Institute; Research Personnel; Research Proposals; Research Training; Resources; Review Committee; Science; Scientist; Series; Students; Testing; Training; Training Activity; Training Programs; Translational Research; Work; Workforce Development; career; career development; catalyst; clinical efficacy; community based participatory research; design; education research; experience; graduate student; implementation barriers; innovation; programs; research and development; student training; undergraduate student

The Translational Endeavor core provides for developing a translational workforce and for providing an awards program to enhance research development within OCTRI. The OCTRI Translational Workforce program includes the highly successful research education and career development programs developed over the past 15 years. Research training programs have been implemented specific to the career development phase: undergraduate students; graduate PhD, MD, DMD, and PharmD students; postdoctoral and clinical fellows; and early faculty. The Human Investigations Program provides training in the competencies of clinical and translational research and underlies all programs. Specific training for students includes the physician-scientist track, a clerkship in clinical and translational research, and the FOLIO program for graduate students. The OCTRI Scholar program provides enhanced mentorship and support to mentored career development awardees to increase the odds of achieving research independence. During the next grant period, we will disseminate these successful training modules to the CTSA consortium, particularly biostatistics and bioinformatics. We will enhance our training for early faculty by creating a research development team that pairs an inexperienced clinician or scientist with an experienced research mentor to design, submit for funding, and implement a research proposal with the assistance of the team; this same team will work to problem solve implementation barriers for early researchers. Finally, we will increase the proportion of clinical research professionals who achieve specific research competencies by strengthening and focusing research staff training through an integrated series of training sessions. The OCTRI Pilots and Clinical Studies program provides investigators with funding and resources to advance their research to the next stage. The Pilot Awards Program also serves as a “living lab” for the design and dissemination of research, process, and evaluation methods that impact the efficiency and efficacy of clinical and translational research. The program comprises four key funding mechanisms: OCTRI Catalyst Awards, OCTRI Community Research Coalition Awards, Strategic Investments, and the Biomedical Innovation Program. Over the next grant period we will expand competitive access to our OCTRI partners. We will add an additional mechanism, the Pathways to Independence Award, for early career researchers. This award will fund research likely to impact their career trajectories. We will test this model experimentally, randomly assigning grantees to receive or not receive a package of intensive workforce development and team science interventions. In addition, we will centralize our already rigorous and transparent review process, forming a single standing review committee for all pilot awards that will incorporate external and cross-CTSA reviewers. The OCTRI Awards Program will continue to refine its successful evaluation approach, disseminating findings widely across the CTSA network and the evaluation community.

翻译奋进核心旨在培养翻译团队并提供奖励 旨在加强 OCTRI 内部研究开发的计划。 OCTRI 转化劳动力计划包括非常成功的研究教育和职业 过去 15 年制定的研究培训计划已得到实施。 具体到职业发展阶段：本科生、博士生、MD、DMD、PharmD； 学生；博士后和临床研究员；以及早期教师。 临床和转化研究能力的培训是所有具体培训的基础。 为学生提供的课程包括医师科学家轨道、临床和转化研究实习以及 OCTRI 学者计划为研究生提供强化的指导和帮助。 支持受指导的职业发展获奖者，以增加实现研究独立的可能性。 在下一个资助期内，我们将向 CTSA 联盟传播这些成功的培训模块， 特别是生物统计学和生物信息学，我们将通过开展一项研究来加强对早期教师的培训。 开发团队将缺乏经验的临床医生或科学家与经验丰富的研究导师配对 在该团队的协助下设计、提交资助并实施研究计划； 将致力于解决早期研究人员实施障碍的问题。最后，我们将增加比例。 通过加强和专注来实现特定研究能力的临床研究专业人员 通过一系列综合培训课程对研究人员进行培训。 OCTRI 试点和临床研究计划为研究人员提供资金和资源以推进 他们的研究进入下一阶段，试点奖励计划也充当了设计和研究的“生活实验室”。 传播影响临床效率和功效的研究、过程和评估方法 该计划包括四个关键资助机制：OCTRI 催化剂奖、 OCTRI 社区研究联盟奖项、战略投资和生物医学创新 在下一个资助期内，我们将扩大对 OCTRI 合作伙伴的竞争性访问。 另一项机制是为早期职业研究人员设立“独立之路奖”。 资助可能影响他们职业轨迹的研究。我们将随机实验测试这个模型。 分配受资助者接受或不接受强化劳动力发展和团队科学的一揽子计划 此外，我们将集中我们已经严格和透明的审查流程，形成一个 所有试点奖项都有一个常设审查委员会，其中包括外部和跨 CTSA 审查员。 OCTRI 奖项计划将继续完善其成功的评估方法，传播研究结果 广泛应用于 CTSA 网络和评估界。