U HAWAII COBRE: TECHNICAL SUPPORT CORE

夏威夷大学 COBRE：技术支持核心

• 批准号: 7610518
• 负责人: VIVEK Ramchandra NERURKAR
• 金额: $ 34.64万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7610518
• 关键词: Bioinformatics; Biometry; Burn injury; Cell Survival; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Containment; Core Facility; Equipment; Floor; Funding; Grant; Hawaii; Hospitals; Human Resources; Immunology; Infectious Diseases Research; Institution; Interviewer; Laboratories; Laboratory Research; Mentors; Molecular; Molecular Biology; Protocols documentation; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Retrovirology; Scintillation Counter; Services; Source; Time; United States National Institutes of Health; University Hospitals; biosafety level 3 facility; experience; improved; medical schools

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Specific Aims: Improve research competitiveness by enhancing the capacity for mentoring and expanding the capability of the technical support infrastructure for infectious disease research. A vital part of the Pacific Center for Emerging Infectious Diseases Research is the Technical Support Core, which provides specific services and optimizes specific protocols to facilitate the successful implementation and completion of the COBRE Research Projects. The COBRE Mentor, Dr. Vivek R. Nerurkar, who oversees the utilization of core services and has overall responsibility for efficiently and effectively managing COBRE technical support resources, directs this Core. The COBRE Technical Support Core principally resides within the RCMI-NCRR supported Retrovirology Research Laboratory (RRL). By utilizing the existing infrastructure and further expanding the existing facility, it is envisioned that duplication of services and equipment will be minimized. Moreover, the COBRE projects will be efficiently served by leveraging access to expensive equipment as well as technological advances that were developed and sustained with NIH support over the past 13 years. One example of such leverage is the immediate access to a flow cytometer, flow sorter, faxitron, scintillation counter, phosphorimager, cell-viability analyzer and the fully equipped and certified BSL-3 facility. Moreover, personnel within the RRL who are supported by non-COBRE funds, have experience in conducting infectious diseases research. It is envisioned that these personnel who form a immediate critical core, will further assist the COBRE investigators technically and scientifically in developing their research projects. One full-time Interviewer and one each part-time Molecular Biologist, Virologist, Bioinformatician, Research Assistant/Bioinformatics, and Flow Cytometrist, staff the COBRE Technical Support Core. The Core consists of three principal technical support services: " Molecular Biology and Immunology Core Facility " Biostatistics and Bioinformatics Core Facility " BSL-3 Containment Facility Since January 2006 when the Molecular Biology and Immunology and the Biostatistics and Bioinformatics core facilities were relocated from the Leahi Hospital and the University of Hawaii at Manoa (UHM) main campus to the 3rd floor of the brand new John A. Burns School of Medicine, Biosciences Building (BSB) in Kakaako, the usage of COBRE cores has dramatically increased. The 250 sq. ft. BSL-3 Containment Facility is still located at the Leahi Hospital. Laboratories of COBRE Core Director Dr. Vivek R. Nerurkar and COBRE PIs Drs. Allison Imrie and Guliz Erdem are located in very close proximity of the COBRE Core Facility on the 3rd floor of the BSB.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此，可以在其他清晰的条目中表示。列出的机构是 对于中心，这不一定是调查员的机构。 具体目的：通过增强指导和扩大技术支持基础设施能力进行传染病研究的能力来提高研究竞争力。 太平洋新兴传染病研究中心的重要组成部分是技术支持核心，该核心提供了特定的服务并优化了特定协议，以促进COBRE研究项目的成功实施和完成。 柯布雷导师Vivek R. Nerurkar博士负责核心服务的利用，总体上负责有效，有效地管理Cobre技术支持资源，并指导了这一核心。 COBRE技术支持核心主要位于RCMI-NCRR支持的逆转录病毒研究实验室（RRL）中。 通过利用现有的基础架构并进一步扩展现有工厂，可以预见，服务和设备的重复将被最小化。 此外，通过利用昂贵的设备以及在过去13年中NIH支持的技术进步以及通过NIH支持的技术进步，可以有效地提供毛绒项目。 这种杠杆作用的一个例子是立即访问流式细胞仪，流动器，faxitron，闪烁计数器，磷光灯，细胞可变性分析仪以及完全配备和经过认证的BSL-3设施。 此外，RRL的人员在非近代基金的支持下具有进行传染病研究的经验。 可以预见的是，这些构成直接关键核心的人员将进一步协助毛cor研究者在技术和科学上进一步开发其研究项目。 一名全职访问者和一位兼职分子生物学家，病毒学家，生物信息学家，研究助理/生物信息学和流式细胞学师的工作人员，是COBRE技术支持核心的工作人员。 核心由三个主要技术支持服务组成： “分子生物学和免疫学核心设施 “生物统计学和生物信息学核心设施 “ BSL-3遏制设施 自2006年1月以来，分子生物学和免疫学以及生物统计学和生物信息学核心设施被搬迁从Leahi医院和Manoa（UHM）主校园的夏威夷大学（UHM）主校园迁至全新的John A. Burns医学院的三楼在卡卡科（Kakaako）的生物科学大楼（BSB），柯布尔岩心的使用量显着增加。 250平方英尺的BSL-3遏制设施仍位于Leahi医院。 Cobre Core主任Vivek R. Nerurkar博士和Cobre Pi s Drs的实验室。 Allison Imrie和Guliz Erdem位于BSB三楼的Cobre Core设施非常接近。