CONT PSTV AIRWAY PRESS&INSLN SENSITIZATION W/ROSIG ON ERECTILE DYSFNCTN W/APNEA

继续 PSTV 气道新闻

• 批准号: 7604427
• 负责人: Margaret E Wierman
• 金额: $ 0.2万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7604427
• 关键词: Affect; Apnea; Computer Retrieval of Information on Scientific Projects Database; Continuous Positive Airway Pressure; Drug usage; Erectile dysfunction; Funding; Grant; Hormones; Institution; Insulin; Insulin Resistance; Non-Insulin-Dependent Diabetes Mellitus; Obstructive Sleep Apnea; Patient Care; Patients; Purpose; Research; Research Personnel; Resources; Sex Functioning; Sleep Apnea Syndromes; Source; Standards of Weights and Measures; United States National Institutes of Health; improved

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to see how obstructive sleep apnea affects erectile function and hormone levels. We are looking at insulin resistance, an underlying cause of type 2 diabetes. Insulin resistance occurs when the body fails to respond properly to the insulin it already produces. This study is examining whether people who have obstructive sleep apnea have insulin resistance that may be worsening their sexual function. We will be treating all patients with continuous positive airway pressure, the standard of care for patients with sleep apnea. In addition, half the patients will receive a drug used initially in the treatment of Type 2 diabetes that helps the body become more sensitive to insulin. We hope that it will improve erectile dysfunction as well.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此，可以在其他清晰的条目中表示。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究的目的是了解阻塞性睡眠呼吸暂停如何影响勃起功能和激素水平。 我们正在研究胰岛素抵抗，这是2型糖尿病的根本原因。 当人体无法正确反应其已经产生的胰岛素时，就会发生胰岛素抵抗。 这项研究正在研究患有阻塞性睡眠呼吸暂停的人是否具有胰岛素抵抗，这可能会使他们的性功能恶化。我们将治疗所有持续气道压力的患者，这是睡眠呼吸暂停患者的护理标准。 此外，一半的患者将收到最初用于治疗2型糖尿病的药物，这有助于人体对胰岛素更敏感。 我们希望它也会改善勃起功能障碍。