Prenatal Social Connection and Disruption During the COVID-19 Pandemic: Effects on Maternal and Infant Health

COVID-19 大流行期间的产前社交联系和中断：对母婴健康的影响

• 批准号: 10187191
• 负责人: Darby E. Saxbe
• 金额: $ 36.12万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-01 至 2026-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10187191
• 关键词: Affect; Age; Anxiety; Anxiety Disorders; Apgar Score; Behavior; Behavioral; Birth; Birth Weight; Buffers; COVID-19; COVID-19 pandemic; Child; Child Health; Child Rearing; Childbirth; Communities; Coronavirus; Data; Data Reporting; Data Set; Development; Disease; Distress; Economics; Enrollment; Extended Family; Family health status; Fathers; Feeling; Fetal Development; Foundations; Fright; Funding; Geographic Locations; Gestational Age; Guidelines; Hair; Health; Height; Home; Hospitals; Hydrocortisone; Incidence; Infant; Infant Development; Infant Health; Infection; Knowledge; Link; Location; Loneliness; Long-Term Effects; Low Birth Weight Infant; Maternal Health; Measures; Mental Depression; Mental Health; Modeling; Mood Disorders; Mothers; National Institute of Child Health and Human Development; Natural experiment; Neurosecretory Systems; Outcome; Parents; Participant; Patient Self-Report; Personal Satisfaction; Persons; Population; Postpartum Period; Pregnancy; Pregnant Women; Premature Birth; Prenatal care; Readiness; Recovery; Reporting; Research; Risk; Risk Factors; Sampling; Schools; Shapes; Social Behavior; Social Distance; Social support; Source; Strategic Planning; Stress; Temperament; Testing; United States; Woman; anxiety symptoms; biopsychosocial factor; cohort; depressive symptoms; experience; follow-up; health economics; healthy pregnancy; in utero; indexing; infant temperament; insight; neurodevelopment; neuroimaging; pandemic disease; perceived stress; postpartum outcome; prenatal; prenatal stress; protective factors; psychological distress; recruit; resilience; social; social factors; stress management; stress resilience; stressor

PROJECT SUMMARY The COVID-19 pandemic has had sweeping effects on pregnant women and their partners. The need to adhere to social distancing guidelines has altered the social connectedness of expectant parents, with effects on stress, loneliness, reduced access to in- person prenatal care, and childbirth support. Social support during pregnancy is known to buffer stress and predict better postpartum outcomes for both new parents and their infants. For example, greater prenatal support has been linked with decreased risk of parental postpartum mood and anxiety disorders, lower incidence of preterm birth and low birth weight, calmer infant temperament, and healthier infant development. Given this evidence, pandemic-induced changes to social connectedness during pregnancy may have long-term effects for new parents and their children. The current proposal leverages the unique natural experiment of the COVID-19 pandemic to examine the maternal and infant health effects of social connectedness among pregnant women and their partners. The CHIRP (Coronavirus, Health, Isolation and Resilience in Pregnancy) study launched in spring 2020 and has enrolled 710 expectant parents who reported on their feelings of social connectedness and support during pregnancy. We will follow up with this cohort three, six, and 12 months after the birth of their child. In addition to collecting self-report data, we will gather hospital birth charts to measure gestational outcomes, and hair cortisol to measure neuroendocrine stress exposure. We also plan to use geocoding to model the social, economic, and health impacts of the pandemic and explore how these impacts shape postpartum outcomes. Our lab has already collected data from another cohort of 200 expectant parents recruited during pregnancy and followed over the transition to parenthood, constituting a pre-pandemic comparison sample with the same measures and timing. We will also conduct a five-year follow-up with children from our pre-pandemic dataset that will incorporate behavioral and neuroimaging measures of neurodevelopment. Our pilot data indicates significantly higher ratings of psychological distress and lower ratings of social support among expectant parents affected by the COVID-19 pandemic. We expect that this project will make important contributions to the study of stress and resilience during pregnancy and its long-term effects on both maternal and infant well-being.

项目概要 COVID-19 大流行对孕妇及其家人产生了广泛影响 合作伙伴。遵守社交距离准则的需要改变了社交 准父母的连通性，对压力、孤独感、接触信息机会减少的影响 人员产前护理和分娩支持。众所周知，怀孕期间的社会支持 缓冲压力并为新父母及其婴儿预测更好的产后结果。 例如，加强产前支持与降低父母患病风险有关。 产后情绪和焦虑障碍，降低早产和低产率 体重、婴儿气质更平静、婴儿发育更健康。鉴于此证据， 大流行引起的怀孕期间社会联系的变化可能会产生长期影响 对新父母及其孩子的影响。 目前的提案利用了 COVID-19 的独特自然实验 大流行病以检查社会联系对孕产妇和婴儿健康的影响 孕妇及其伴侣。 CHIRP（冠状病毒、健康、隔离和 妊娠复原力）研究于 2020 年春季启动，已招募 710 名孕妇 家长们报告了他们在学习期间对社会联系和支持的感受 怀孕。我们将在他们的孩子出生后 3、6 和 12 个月对这群人进行跟踪调查 孩子。除了收集自我报告数据外，我们还会收集医院出生图表来衡量 妊娠结局和头发皮质醇来测量神经内分泌压力暴露。我们也 计划使用地理编码来模拟大流行的社会、经济和健康影响 并探讨这些影响如何影响产后结果。我们实验室已经收集了 来自另一组 200 名准父母在怀孕期间招募并跟踪的数据 在向为人父母的过渡过程中，构成了大流行前的比较样本 相同的措施和时间安排。我们还将对我们的孩子进行为期五年的随访 大流行前数据集将纳入行为和神经影像测量 神经发育。 我们的试点数据表明，心理困扰的评级明显较高，而心理困扰的评级较低 受 COVID-19 大流行影响的准父母的社会支持评级。我们 期望该项目将为压力和复原力的研究做出重要贡献 怀孕期间的情况及其对孕产妇和婴儿健康的长期影响。