The Epidemiology of Hospitalized Postpartum Depression

住院产后抑郁症的流行病学

基本信息

批准号：
7616703
负责人：
David A Savitz
金额：
$ 1.42万
依托单位：
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-04-01 至 2010-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7616703
关键词：
Address Affect Age Distribution Behavioral Birth Breast Feeding Censuses Characteristics Child Cognitive Data Death Records Development Disadvantaged Disease Distress Education Emotional Epidemiology Ethnic Origin Foundations Frequencies Future Gender Geographic Locations Gestational Diabetes Hospitalization Hospitals Incidence Infant Infant Care Infant Health Interruption Intervention Intervention Studies Knowledge Lead Link Location Marital Status Maternal Age Measures Mothers Neighborhoods New York New York City Newborn Infant Outcome Pattern Population Heterogeneity Postpartum Depression Postpartum Period Pre-Eclampsia Pregnancy Pregnancy Complications Premature Birth Prenatal care Prevalence Prevention Prospective Studies Psyche structure Race Records Relative (related person)Reporting Research Resources Role Sampling Services Smoking Status Social Work Socioeconomic Status Source Time Urbanization Well in self Woman base clinically significant cost critical period depression design follow-up high risk infant death maternal depression parity payment population based psychotic depression public health relevance social socioeconomics trend

项目摘要

DESCRIPTION (provided by applicant): The epidemiological characteristics of severe postpartum depression requiring hospitalization have not been described. Based on the limited data available, hospitalized postpartum depression comprises approximately 5 percent of all cases and appears to disproportionately afflict socioeconomically disadvantaged women at the extremes of the maternal age distribution. However, a current and reliable estimate of the frequency of severe postpartum depression and its pattern of occurrence in relation to social, demographic, behavioral, and infant health characteristics is not available. We propose to conduct a highly efficient, yet comprehensive and population-based assessment of hospitalized postpartum depression in the large and diverse population of the State of New York by linking publicly available data resources. Using hospital discharge data, we will follow each woman forward in time for one year following births that occur in the state from 1995 through 2004. By linking delivery and depression hospital discharge records, we can estimate the prevalence and incidence of severe postpartum depression with a high degree of comprehensiveness and accuracy. We will link these data to the 2000 Census to evaluate neighborhood socioeconomic and urbanization factors, and infant hospitalization and death records. With this unique data resource, we will (1) Describe the epidemiology of hospitalized postpartum depression by identifying patterns in relation to maternal sociodemographic characteristics and geographic location; (2) Examine the relation between infant health and hospitalization for postpartum depression; and (3) Examine the relation between common complications of pregnancy, including gestational diabetes mellitus, preeclampsia, and cesarean delivery, and hospitalization for postpartum depression. This research will provide a needed basis on which to focus future etiologic and intervention research by identifying the predictors and defining the characteristics of those at highest risk for severe postpartum depression. PUBLIC HEALTH RELEVANCE: Postpartum depression requiring hospitalization is a potentially catastrophic consequence of pregnancy that adversely affects both the mother and the child and frequently necessitates the intervention of social services to provide care for the infant. Moreover, the interruption of mother-child bonding during this critical period may result in long term consequences for the child's cognitive and emotional well- being, which in itself carries a significant social cost. By clearly identifying the epidemiologic patterns of occurrence, this study will provide needed guidance regarding the design and conduct of detailed etiologic studies of the social, behavioral, and biomedical causes of severe postpartum depression.

描述（由申请人提供）：尚未描述需要住院的严重产后抑郁症的流行病学特征。基于可用的数据有限，住院的产后抑郁症约占所有病例的5％，并且在母亲年龄分布的极端情况下似乎不成比例地折磨社会经济处境不利的妇女。但是，目前尚无对社会，人口，行为和婴儿健康特征有关的严重产后抑郁频率及其发生模式的频率的估计。我们建议通过连接公开可用的数据资源来对纽约州大而多样化的纽约州大量人口进行高效但全面和基于人群的基于人群的评估。使用医院出院数据，我们将在1995年至2004年在该州出生后的一年前及时跟踪每位妇女。通过将分娩和抑郁症医院的出院记录联系起来，我们可以估计严重的产后抑郁症的患病率和发生率和高度的全面性和准确性。我们将将这些数据与2000年的人口普查联系起来，以评估社区社会经济和城市化因素，以及婴儿住院和死亡记录。借助这种独特的数据资源，我们将（1）通过识别与母体社会人口统计学特征和地理位置有关的模式来描述住院产后抑郁症的流行病学；（2）检查婴儿健康与产后抑郁症之间的关系；（3）检查妊娠常见并发症（包括妊娠糖尿病，前宾夕法尼亚和剖宫产）与产后抑郁症的住院之间的关系。这项研究将提供一个必要的依据，通过确定预测因子并定义那些严重产后抑郁症风险最高的人的特征，以重点关注未来的病因和干预研究。公共卫生相关性：需要住院的产后抑郁症是怀孕的潜在灾难性后果，会对母亲和孩子产生不利影响，并且经常需要社会服务的干预以为婴儿提供护理。此外，在这个关键时期，母子纽带的中断可能会对孩子的认知和情感福祉产生长期后果，这本身就带来了巨大的社会成本。通过清楚地识别发生的流行病学模式，这项研究将为有关严重产后抑郁症的社会，行为和生物医学原因的详细病因学研究提供所需的指导。