HEART FAILURE MODELING IN RABBIT

兔子心力衰竭模型

• 批准号: 7601722
• 负责人: Alan J Garfinkel
• 金额: $ 0.18万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7601722
• 关键词: Binding; Biological Models; Cause of Death; Computer Retrieval of Information on Scientific Projects Database; Diffusion; Equation; Funding; General Population; Grant; Heart; Heart failure; Institution; Modeling; Oryctolagus cuniculus; Reaction; Research; Research Personnel; Resources; Source; Tissues; United States National Institutes of Health; Work; insight; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Heart failure is a leading cause of death in the general population. Rabbit models are important in providing insights into the factors contributing to heart failure. Previous experiments have indicated that: rectilinear waves, governed by reaction-diffusion partial differential equations, can become unstable and break up, even in perfectly homogeneous tissue, due to electrical instabilities. Current work aims to develop better models to describe the molecular interactions using reaction-diffusion PDEs using rabbit heart as the modeling system.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 心力衰竭是普通人群死亡的主要原因。兔子模型对于提供有关导致心力衰竭的因素的见解很重要。先前的实验表明：由反应扩散部分微分方程控制的直线波可能会变得不稳定和破裂，即使在完全均匀的组织中，由于电不稳定性。当前的工作旨在开发更好的模型，以使用兔心作为建模系统使用反应扩散PDE来描述分子相互作用。