INTRACELLULAR HEAVY METAL LOCALIZATION IN ARABIDOPSIS

拟南芥细胞内重金属定位

• 批准号: 7601073
• 负责人: JULIAN I SCHROEDER
• 金额: $ 1.09万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7601073
• 关键词: Affect; Arabidopsis; Cadmium; Computer Retrieval of Information on Scientific Projects Database; Copper; Funding; Glutathione; Grant; Heavy Metals; Institution; Localized; Mouse-ear Cress; Peptides; Plant Roots; Plants; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; mutant; phytochelatin; Affect; Arabidopsis; Cadmium; Computer Retrieval of Information on Scientific Projects Database; Copper; Funding; Glutathione; Grant; Heavy Metals; Institution; Localized; Mouse-ear Cress; Peptides; Plant Roots; Plants; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; mutant; phytochelatin

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. During the course of investigating the role of phytochelatins, glutathione-derived peptides, in cadmium inactivation and translocation in plants it was found that the phytochelatin deficient mutant cad1-3 (Arabidopsis thaliana, Col ecotype) overaccumulates copper in roots. Such accumulation is dependent upon cadmium exposure and does not affect the copper content in shoots, either before or after cadmium exposure. It is intended to use the NCMIR to localize the intracellular compartment in which copper is being accumulated.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 在研究植物chelatins（谷胱甘肽衍生的肽）在镉灭活和易位中的作用的过程中，发现植物毒素缺乏的突变体cad1-3（拟南芥thaliana，col Ecotype，Col Ecotype）使铜中的铜过度占用。这种积累取决于镉的暴露，并且在镉暴露之前或之后不影响芽中的铜含量。它旨在使用NCMIR来定位蓄积铜的细胞内室。