ULTRASOUND MEASUREMENT OF TUMOR MICROCIRCULATION AND PERFUSION

肿瘤微循环和灌注的超声测量

• 批准号: 7601203
• 负责人: Mark Wesley DeWhirst
• 金额: $ 1万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7601203
• 关键词: Animals; Architecture; Computer Retrieval of Information on Scientific Projects Database; Fever; Funding; Grant; Histology; Image; Institution; Life; Liposomes; Measurement; Microcirculation; Perfusion; Pharmaceutical Preparations; Radiation; Research; Research Personnel; Resources; Source; Tumor Volume; Ultrasonography; United States National Institutes of Health; animal data; hyperthermia treatment; radiation effect; tumor; tumor growth

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Live animal data only. We are doing a serial study to look at the effect of radiation, hyperthermia, and drug-containing liposomes on tumor growth delay. We plan to sacrifice animals for histology, but would like images of tumor volume and doppler prior and post treatment to observed changes in tumor perfusion. Idealy when the micro bubbles are available we would like to image the animals microcirculation to look for architecture changes that can result from the use of radiation and/or drug.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 仅活动物数据。我们正在进行一项序列研究，以研究辐射，热疗和含药物脂质体对肿瘤生长延迟的影响。我们计划为组织学牺牲动物，但希望在观察到的肿瘤体积和多普勒之前的图像和多普勒之前的图像，以观察到肿瘤灌注的变化。 有思想的是，当有微气泡可用时，我们想对动物的微循环进行图像，以寻找可能由辐射和/或药物使用的结构变化。