A MOLECULAR FOUNDATION FOR THE TREATMENT OF ARSENIC POISONING IN BANGLADESH

孟加拉国治疗砷中毒的分子基础

• 批准号: 7598146
• 负责人: GRAHAM N GEORGE
• 金额: $ 0.14万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7598146
• 关键词: Affect; Area; Arsenic; Arsenic Poisoning; Bangladesh; Chronic; Computer Retrieval of Information on Scientific Projects Database; Foundations; Funding; Grant; Institution; Molecular; Poisoning; Research; Research Personnel; Resources; Roentgen Rays; Source; Spectrum Analysis; Toxic effect; United States National Institutes of Health; Work; absorption; selenium deficiency; Affect; Area; Arsenic; Arsenic Poisoning; Bangladesh; Chronic; Computer Retrieval of Information on Scientific Projects Database; Foundations; Funding; Grant; Institution; Molecular; Poisoning; Research; Research Personnel; Resources; Roentgen Rays; Source; Spectrum Analysis; Toxic effect; United States National Institutes of Health; Work; absorption; selenium deficiency

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In what has been called the world¿s worst mass poisoning, between 35 and 70 million people are affected by chronic low-level arsenic poisoning in Bangladesh and surrounding areas. We have previously suggested that this poisoning is not directly due to the toxic effects of arsenic, but is instead primarily due to arsenic-induced selenium deficiency. We plan to build on our earlier work to provide a molecular foundation for the treatment of chronic low-level arsenic poisoning in Bangladesh and other affected areas. X-ray absorption spectroscopy (XAS) holds the key to these discoveries.

该副本是使用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这是调查员的机构。 在所谓的世界最严重的大规模中毒中，孟加拉国及周边地区的慢性低级砷中毒受到了35至7000万人的影响。我们以前已经提出，这种中毒不是直接是由于砷的毒性作用，而是由于砷引起的硒缺乏症而起来的。我们计划以早期的工作为基础，为孟加拉国和其他受影响地区的慢性低水平砷中毒提供分子基础。 X射线抽象光谱（XAS）是这些发现的关键。