SETAC North America Non-Target Analysis in Environmental Risk Assessment Focus Topic Meeting

SETAC北美环境风险评估非目标分析焦点专题会议

• 批准号: 9914759
• 负责人: Tamar Schlekat
• 金额: $ 1.5万
• 依托单位: SOCIETY/ENVIRON/ TOXICOLOGY/CHEMISTRY NA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-05 至 2022-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9914759
• 关键词: Academia; Address; Analytical Chemistry; Applications Grants; Archives; Area; Benchmarking; Biological; Chemicals; Data; Data Analyses; Data Science; Development; Discipline; Ecosystem; Engineering; Environmental Monitoring; Environmental Pollution; Environmental Risk Factor; Evaluation; Fees; Funding; Goals; Government; Health; Home environment; Human; Image; Industry; International; Journals; Knowledge; Modeling; Monitor; National Institute of Environmental Health Sciences; Nonprofit Organizations; North America; North Carolina; Occupations; Outcome; Output; Peer Review; Performance; Private Sector; Publications; Recording of previous events; Regulation; Reporting; Reproducibility; Research; Risk Assessment; Safety; Sampling; Science; Scientist; Series; Slide; Societies; Structure; Superfund; Toxic effect; Toxicology; Travel; Vision; anthropogenesis; cheminformatics; cost; data archive; data tools; environmental chemistry; environmental stressor; environmental toxicology; experimental study; instrumentation; journal article; medical specialties; meetings; posters; programs; statistics; symposium; tool

SETAC North America Focused Topic Meeting Non-Targeted Analysis for Comprehensive Environmental Assessment Durham Convention Center, Durham, North Carolina, USA May 26-31, 2020 Project Summary NIEHS support is sought for the SETAC North America Focused Topic Meeting “Non-Targeted Analysis for Comprehensive Environmental Assessment.” The meeting priority is to advance sub-disciplines involved in high-throughput identification, scientific study, and regulation of chemicals in environmental and biological media relevant to human and ecosystem health. The meeting will gather experts to report on recent advances in the field and identify significant research needs hindering the wide-spread implementation and use of non-targeted analysis results. To meet the proposed meeting’s objectives, we will pursue the following specific goals: 1. Provide a forum for professionals from different disciplines (including data science and statistics, (eco-)toxicology, analytical and environmental chemistry, cheminformatics, exposure, toxicity, and risk assessment) and from many backgrounds (academia, industry, government, and non-profit organizations) to come together to discuss and advance the state of the knowledge in the field; 2. Develop a framework for compound identification prioritization in non-targeted analysis of environmental and biological samples; 3. Propose benchmarks for analytical and data analyses, performance, and publication; 4. Identify knowledge gaps and shortcomings related to the reproducible acquisition, reporting and archiving of data generated by non-targeted analysis experiments; 5. Critically assess strengths and practical limitations of using non-targeted analysis in environmental monitoring, exposomics research, and chemical risk assessment. These goals will be achieved by convening leading international experts diverse research fields, job activities, and organizations. Funds being sought through this grant application will be used to offset the cost of the attendance for 12 invited experts and to include registration fees and a travel stipend. The meeting will span five days consisting of a combination of platform and poster sessions, breakout groups, panel discussions, and tool demonstrations, and is expected to attract 200 experts. The meeting technical program will cover four main topics: 1. State of the science in non-targeted analysis: instrumentation, data evaluation, monitoring application 2. Prioritizing unknowns for identification: new analytes, transformation products and metabolites 3. Tools for data analysis and beyond: statistics, exposure, toxicity, modeling 4. Looking ahead: benchmarks, knowledge gaps, and wide-spread implementation Meeting outcomes include at least one peer-reviewed journal article to summarize the state-of- the-science and capture discussions and ideas. We also expect to develop a journal article series on the topic from submissions by presenters. Further, poster and slide images from meeting presentation will be archived.

SETAC北美聚焦主题会议 综合环境评价非针对性分析 达勒姆会议中心，达勒姆，北卡罗来纳州，美国 2020年5月26-31日 项目概要 SETAC 北美聚焦主题会议“非针对性”寻求 NIEHS 支持 会议重点是推进综合环评分析。” 涉及高通量鉴定、科学研究和调控的子学科 与人类和生态系统健康相关的环境和生物介质中的化学品。 会议将聚集专家报告该领域的最新进展并确定重大进展 研究需求阻碍了非针对性分析的广泛实施和使用 结果。 为了实现拟议会议的目标，我们将追求以下具体目标： 1. 为不同学科（包括数据科学和 统计学、（生态）毒理学、分析和环境化学、化学信息学、 暴露、毒性和风险评估）并且来自许多背景（学术界、 行业、政府和非营利组织）聚集在一起讨论和 提高该领域的知识水平； 2. 开发非靶向分析中化合物识别优先级的框架 环境和生物样本； 3. 提出分析和数据分析、绩效和出版的基准； 4. 确定与可重复采集相关的知识差距和缺点， 非目标分析实验生成的数据的报告和归档； 5. 批判性地评估使用非目标分析的优势和实际局限性 环境监测、暴露组学研究和化学品风险评估。 这些目标将通过召集不同研究领域的领先国际专家来实现， 将使用通过本补助金申请寻求的工作活动和组织。 抵消 12 名特邀专家的出席费用，并包括注册费和 会议为期五天，包括平台和旅行津贴。 海报会议、分组讨论、小组讨论和工具演示，预计 吸引200名专家。 会议技术议程将涵盖四个主要议题： 1. 非靶向分析的科学现状：仪器、数据评估、监测 应用 2. 优先识别未知因素：新分析师、转型产品和 代谢物 3. 数据分析及其他工具：统计、暴露、毒性、建模 4. 展望未来：基准、知识差距和广泛实施 会议成果包括至少一篇经过同行评审的期刊文章来总结现状 我们还希望撰写一篇期刊文章。 演讲者提交的有关该主题的系列此外，海报和幻灯片图像来自。 会议演示文稿将被存档。