OZONE EXPOSURE AND DOSE DELIVERED TO HUMAN LUNGS

臭氧暴露和输送到人肺的剂量

• 批准号: 7625816
• 负责人: James S Ultman
• 金额: $ 0.65万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7625816
• 关键词: Antioxidants; Automobile Exhaust; Breathing; Computer Retrieval of Information on Scientific Projects Database; Dose; Excision; Funding; Gases; Grant; Human; Institution; Irritants; Lung; Nitric Oxide; Nose; Ozone; Research; Research Personnel; Resources; Respiratory System; Source; Thinking; United States National Institutes of Health; ozone exposure; pollutant

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Ozone is an irritant, pollutant gas that results from automobile exhaust. We are trying to understand how inhaled ozone is absorbed in the respiratory system and how the respiratory system responds to the absorbed ozone. We think that continuous breathing of ozone influences the removal of ozone by the nose. In particular, we expect that natural antioxidants such as nitric oxide will be temporarily depleted so that ozone removal by the nose will decrease as ozone exposure progresses.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 臭氧是一种由汽车尾气产生的刺激性污染气体。我们试图了解吸入的臭氧如何被呼吸系统吸收以及呼吸系统如何对吸收的臭氧做出反应。 我们认为持续呼吸臭氧会影响鼻子对臭氧的清除。 特别是，我们预计一氧化氮等天然抗氧化剂将暂时耗尽，因此随着臭氧暴露的进展，鼻子去除的臭氧将会减少。