Development of a Geographical Momentary Assessment Informed Trauma Intervention to Improve ART Adherence and Viral Suppression in Violence-Affected Persons Living with HIV

制定地理瞬时评估知情创伤干预措施，以提高受暴力影响的艾滋病毒感染者的抗逆转录病毒治疗依从性和病毒抑制

• 批准号: 9913191
• 负责人: Gretchen Clum
• 金额: $ 21.84万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-10 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9913191
• 关键词: Address; Adherence; Adopted; Affect; Alcohol or Other Drugs use; Alcohols; Caring; Cellular Phone; Clinical; Cognition; County; Couples; Crime; Data; Development; Dose; Ecological momentary assessment; Epidemic; Evidence based intervention; Exposure to; Failure; Frequencies; Geography; Goals; Green space; HIV; Health; Individual; Intervention; Link; Literature; Longitudinal cohort; Louisiana; Mediating; Mediation; Mediator of activation protein; Mental Health; Methodology; Methods; Moods; Morbidity - disease rate; Motivation; Neighborhoods; Outcome; Pathway interactions; Personal Satisfaction; Persons; Pharmaceutical Preparations; Post-Traumatic Stress Disorders; Primary Health Care; Psychosocial Factor; Recording of previous events; Regimen; Research; Risk Factors; Self Efficacy; Stress and Coping; Symptoms; Technology; Testing; Trauma; United States National Institutes of Health; Violence; Viral; Work; alcohol outlet density; antiretroviral therapy; anxiety symptoms; barrier to care; care outcomes; contextual factors; coping; density; diaries; evidence base; experience; improved; mobile application; mobile computing; mortality; negative mood; novel; pill; preference; protective factors; psychosocial; secondary outcome; side effect; social; social cognitive theory; social factors; sociodemographics; theories; therapy adherence

Abstract: Violence-affected persons living with HIV (PLWH) are less likely to successfully adhere to medication regimens, engage in care, and achieve sustained viral suppression. Technology-delivered interventions are necessary to meet the needs of violence affected PLWH (VAPLWH). Currently, there are no mobile interventions for VAPLWH tailored to their daily experiences. This project uses Geographical Ecological Momentary Assessment (GEMA) to identify the daily activity spaces and psychosocial factors that influence engagement in care for VAPLWH. The impact of frequency and timing of violence experienced will be examined in these relationships. Formative work will be conducted to understand VAPLWH needs and preferences for a mobile intervention. The goal is to develop a trauma-informed mobile intervention by adapting an evidence-based intervention, Living in the Face of Trauma (LIFT) and adding novel GEMA identified targets for intervention. Feasibility and acceptability of the intervention will be tested using mixed methods, and a pilot test of the intervention will be conducted to examine preliminary efficacy on adherence and care engagement. Limitations in prior research are examined by using GEMA to identify contextual and situational factors on care in PLWH, explore potential modifying factors related to violence and socio-demographics, and incorporate these into a mobile intervention to improve mental health and address barriers to care for VAPLWH.

摘要：受暴力影响的艾滋病毒感染者 (PLWH) 成功康复的可能性较小 坚持用药方案、进行护理并实现持续的病毒抑制。 为了满足受暴力影响的艾滋病毒感染者的需求，有必要采取技术干预措施 （VAPLWH）。目前，还没有针对 VAPLWH 的日常生活量身定制的移动干预措施 经验。该项目使用地理生态瞬时评估（GEMA） 确定影响护理参与度的日常活动空间和社会心理因素 VAPLWH。所经历的暴力的频率和时间的影响将在 这些关系。将开展形成性工作，以了解 VAPLWH 的需求和 移动干预的偏好。目标是开发一种创伤信息移动设备 通过采用循证干预措施进行干预，生活在创伤中 (LIFT) 并添加新的 GEMA 确定的干预目标。可行性和可接受性 干预措施将采用混合方法进行测试，并将对干预措施进行试点测试 旨在检查依从性和护理参与度的初步效果。局限性 通过使用 GEMA 来检查先前的研究，以确定相关的背景和情境因素 艾滋病毒感染者护理，探索与暴力和社会人口统计相关的潜在改变因素， 并将这些纳入移动干预措施中，以改善心理健康并解决障碍 照顾 VAPLWH。