NONPHARMACOLOGICAL TREATMENT OF COMORBID ANXIETY AND HYPERTENSION

共病焦虑和高血压的非药物治疗

• 批准号: 7607697
• 负责人: GRETCHEN A BRENES
• 金额: $ 6.18万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607697
• 关键词: Adjuvant; Anxiety; Blood Pressure; Breathing; Computer Retrieval of Information on Scientific Projects Database; Condition; Control Groups; Devices; Elderly; Exhalation; Face; Funding; Grant; Hypertension; Institution; Intervention; Mental Health; Pharmacological Treatment; Population; Purpose; Quality of life; Randomized; Research; Research Personnel; Resources; Source; Staging; Symptoms; Testing; United States National Institutes of Health; experience

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hypertension and anxiety are two problems that many older adults face and that have significant health-related consequences. Over 60% of older adults have hypertension and up to 40% experience symptoms of anxiety. Hypertension and anxiety are frequently comorbid conditions. Although pharmacological treatments have demonstrated efficacy in reducing blood pressure, there is still a large population whose blood pressure remains uncontrolled. Similarly, among older adults, mental health problems, including anxiety, frequently go undetected and untreated, resulting in poorer quality of life. However, no one has examined the efficacy of a treatment for comorbid hypertension and anxiety. Thus, the purpose of this proposal is to test an adjuvant nonpharmacological intervention for the combined reduction of blood pressure and anxiety symptoms. The intervention consists of ResPerate, a device that regulates breathing by prolonging exhalation. Thirty two older adults (greater than or equal to 65 years) with mild stage 1 uncontrolled hypertension (SBP 140-159 mm Hg) and symptoms of anxiety will be randomized into one of two conditions: nonpharmacological treatment group (ResPerate) and control group. The results of this study will be used to conduct a larger trial of nonpharmacological interventions for comorbid anxiety and hypertension.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 中心，不一定是研究者的机构。 高血压和焦虑是许多老年人面临的两个问题，并且会产生严重的健康相关后果。 超过 60% 的老年人患有高血压，高达 40% 的老年人有焦虑症状。 高血压和焦虑症常常是共病。 尽管药物治疗已被证明可以有效降低血压，但仍有大量人群的血压仍未得到控制。 同样，在老年人中，包括焦虑在内的心理健康问题经常未被发现和治疗，从而导致生活质量下降。 然而，没有人研究过治疗高血压和焦虑症的疗效。 因此，该提案的目的是测试一种辅助非药物干预措施，以联合降低血压和焦虑症状。干预措施包括 ResPerate，这是一种通过延长呼气来调节呼吸的设备。 32 名患有轻度 1 期未控制高血压 (SBP 140-159 mm Hg) 和焦虑症状的老年人（大于或等于 65 岁）将被随机分为两种情况之一：非药物治疗组 (ResPerate) 和对照组。 这项研究的结果将用于针对共病焦虑和高血压进行更大规模的非药物干预试验。