ShEEP Request for Small Animal Magnetic Resonance Imaging System

ShEEP 请求小动物磁共振成像系统

• 批准号: 9910077
• 负责人: Patrick J Frost
• 金额: --
• 依托单位: VA GREATER LOS ANGELES HEALTHCARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9910077
• 关键词: 3-Dimensional; Alzheimer' s Disease; Amplifiers; Anesthesia procedures; Animal Experimentation; Animals; Award; Beds; Behavioral Research; Bioluminescence; Brain; Brain imaging; Caliber; Clinical; Collaborations; Complex; Computer software; Core Facility; Critical Care; Data; Diagnostic radiologic examination; Disease; Dose; Epilepsy; Equipment; Fluorescence; Foundations; Funding; Gases; Gastroenterology; Grant; Head; Healthcare; Healthcare Systems; Heart; Human; Image; Imagery; Imaging Techniques; Imaging technology; Individual; Industry; Infrastructure; Injury; Investigation; Lead; Liver; Los Angeles; Lung; Magnetic Resonance Imaging; Metabolic Diseases; Mission; Modality; Morphology; Mus; Nephrology; Noise; Operative Surgical Procedures; Organ; PET/CT scan; Pancreas; Patients; Peer Review; Principal Investigator; Privatization; Productivity; Protocols documentation; Publications; RF coil; Rattus; Research; Research Personnel; Research Project Grants; Rodent; Roentgen Rays; Series; Sheep; Site; Sleep Disorders; Standardization; System; Tissues; Translations; Traumatic Brain Injury; Tumor Biology; United States National Institutes of Health; Urology; Veterans; Work; animal imaging; base; bench to bedside; bone; clinical care; clinical imaging; clinical translation; contrast imaging; imaging capabilities; imaging facilities; imaging modality; imaging platform; imaging study; imaging system; improved; interest; molecular imaging; neuromuscular system; operation; optical imaging; pre-clinical; pre-clinical research; programs; soft tissue; success; systems research; tumor immunology; whole body imaging

The acquisition of the MR Solutions (MRS)-3017 series MRI (3T/17cm bore) imaging system will directly benefit the VA Greater Los Angeles Healthcare System's (VAGLAHS) research program and lead to biomedical advancements that will benefit the overall health care provide to our Veterans. The principal investigator (Dr. Frost) has established a state-of-the-art Small Animal Imaging Core at VAGLAHS that includes optical imaging/X-Ray and PET/CT imaging-platforms. Our Imaging Core has been instrumental in facilitating research at VAGLAHS, which has led to multiple peer reviewed publications and grant awards. The capability provided by the MR Solutions (MRS)-3017 system for performing longitudinal MRl-based studies on small animals will profoundly impact upon the success of VA-supported projects in basic, translational and preclinical biomedical/behavioral research. We have identified a group of VA-funding research projects/studies will benefit from the acquisition of MRI imaging technolgy. These projects include, but are not limited to, the fields of immunology/tumor biology, traumatic brain injury (TBI), Alzheimer's disease (AD), sleep-disorders, epilepsy, metabolic disease, gastroenterology, nephrology, urology, and surgery. !

MR Solutions（MRS）-3017系列MRI（3T/17cm口径）成像系统的收购将直接 使 VA 大洛杉矶医疗系统 (VAGLAHS) 研究计划受益，并导致 生物医学的进步将有利于为我们的退伍军人提供整体医疗保健。校长 研究人员（Frost 博士）在 VAGLAHS 建立了最先进的小动物成像核心 包括光学成像/X 射线和 PET/CT 成像平台。我们的成像核心在以下方面发挥了重要作用： 促进 VAGLAHS 的研究，这导致了多项同行评审的出版物和资助奖项。这 MR Solutions (MRS)-3017 系统提供的功能，用于执行基于 MRl 的纵向研究 小动物将对 VA 支持的基础、转化和项目的成功产生深远影响 临床前生物医学/行为研究。我们已经确定了一组 VA 资助的研究项目/研究 将受益于MRI成像技术的获得。这些项目包括但不限于 免疫学/肿瘤生物学、创伤性脑损伤 (TBI)、阿尔茨海默病 (AD)、睡眠障碍、 癫痫、代谢疾病、胃肠病学、肾脏病学、泌尿外科和外科。 ！