ASPERGILLLUS ANGIONVASION AND DISSEMINATION

曲霉菌的血管侵袭和传播

• 批准号: 7606110
• 负责人: Deborah Krakow
• 金额: $ 0.69万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7606110
• 关键词: Aspergillosis; Aspergillus fumigatus; Computer Retrieval of Information on Scientific Projects Database; Endothelial Cells; Funding; Grant; Harvest; Human; Institution; Invasive; Pathogenesis; Process; Purpose; Research; Research Personnel; Research Project Grants; Resources; Source; Umbilical cord structure; United States National Institutes of Health; Veins; fungus; tissue culture

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research project is to study the interactions of the fungus, Aspergillus Fumigatus, with endothelial cells. Our hypothesis is that the interactions of A. Fumigatus with endothelial cells during the process of angioninvasion are central to the pathogenesis of invasive Aspergillosis. For the proposed studies, the endothelial cells will be harvested from the veins within human umbilical cords and grown in tissue culture.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 该研究项目的目的是研究真菌，曲霉曲霉与内皮细胞的相互作用。 我们的假设是，在敏化过程中，富马图斯与内皮细胞的相互作用对于侵袭性曲霉菌病的发病机理至关重要。对于拟议的研究，内皮细胞将从人脐带中的静脉收获，并在组织培养中生长。