Continued development of WHONET for surveillance of infections & drug resistance

继续开发用于监测感染的 WHONET

• 批准号: 7667907
• 负责人: JOHN STELLING
• 金额: $ 32.07万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7667907
• 关键词: Algorithms; Antimicrobial Resistance; Area; Automation; Basic Science; Boston; Clinical; Collaborations; Communicable Diseases; Communities; Computer Assisted; Computer Systems; Computer software; Containment; Country; Data; Data Element; Data Files; Data Security; Detection; Development; Disease Outbreaks; Documentation; Drug resistance; Effectiveness; Epidemiologist; Epidemiology; Event; Food; Food Microbiology; Fostering; Goals; Government; Health Policy; Healthcare; Imagery; Infection; Infection Control; Informatics; Information Resources; Information Technology; Intervention; Investigation; Laboratories; Maintenance; Medical Informatics; Microbiology; Monitor; Multi-Drug Resistance; Multiple drug resistant Mycobacteria Tuberculosis; Notification; Online Systems; Ontology; Paper; Patients; Policies; Population; Public Health; Research; Research Infrastructure; Research Personnel; Resources; Serologic tests; Site; Social Welfare; System; Test Result; Time; Translating; Update; Virus; World Health Organization; abstracting; antimicrobial drug; authority; base; computerized data processing; data management; data sharing; design; drug resistant microorganism; experience; flexibility; improved; methicillin resistant Staphylococcus aureus; microbial; national surveillance; pathogen; repository; software development; surveillance network; tool; transmission process; trend; user-friendly

DESCRIPTION (provided by applicant): Development of WHONET for Surveillance of Infections and Drug Resistance John Stelling, MD, MPH Project Summary/Abstract The continued emergence of infectious diseases, newly identified pathogens, and multi-drug resistant microorganisms, such as MRSA, VRE, and MDR-TB, is a global priority which threatens patient welfare worldwide and drains limited healthcare resources. Yet the effectiveness of public health strategies for containment and the feasibility of government mandates to track and decrease infections is limited by inadequate tools and information bases for action. The existing, yet dispersed, repositories of test results locked into paper logbooks and incompatible computer systems in microbiology laboratories worldwide constitutes a complexly rich, yet largely untapped resource for tracking the emergence, transmission, and evolutionary spread of microbial populations. With four decades of experience in the development of software to track emerging trends in antimicrobial resistance, our team at the WHO Collaborating Centre for Surveillance of Antimicrobial Resistance, Boston, in coordination with the national, regional, and world headquarters of the World Health Organization, has been a leader in mobilizing and normalizing this information resource to support coordinated scientific investigations and public health action. A cornerstone of our efforts has been the development and dissemination of the WHONET software, a flexible, sophisticated, user-friendly tool for the management and analysis of microbiology test results. WHONET is utilized in over 90 countries by researchers, microbiologists, clinicians, public health epidemiologists, and national surveillance coordinators to manage, primarily at local and national level, results from over 1200 clinical, public health, veterinary, food, and academic laboratories for applications in basic science, clinical, and operational research; public health policy; clinical-decision support; and laboratory capacity- building. The objectives of this proposal are: a) to provide ongoing support to the existing WHONET software while integrating the latest in appropriate information technologies, ontologies, and informatics standards; b) to introduce significant enhancements to the WHONET analysis features in the areas of outbreak detection, data visualization, automation, notification, and information flow, and; c) to increase the effective utilization of WHONET by existing software users, to expand its use into new technical and geographical areas, and to promote data sharing in collaborative research networks. These developments will enhance the scientific and public health impact of our efforts and foster the strategic infrastructure required for collaborative research in developing and assessing infection and antimicrobial resistance containment interventions. Project Narrative: The continued emergence of infectious diseases, newly identified pathogens, and multi-drug resistant microorganisms is a global priority which threatens patient welfare worldwide and drains limited healthcare resources. The WHONET software, utilized in over 90 countries, provides researchers and public health authorities with tools for track emerging trends in infection and drug resistance and to develop and assess interventions for containment and control. The goal of this project is to expand WHONET in the areas of data sharing, outbreak detection, alert notification, and collaborative research in public health and scientific surveillance networks.

描述（由申请人提供）：开发用于监视感染和耐药性的WHONET，医学博士John Stelling，MPH项目摘要/摘要持续出现感染疾病，新鉴定的病原体和多药耐药的微生物，例如MRSA，MRSA，VRE，VRE和MDR-TB是全球优先事项，它威胁到全球患者福利，并耗尽了有限的医疗资源。然而，公共卫生策略对遏制的有效性以及政府要求追踪和减少感染的可行性受到工具和信息基础不足的行动限制。在全球微生物学实验室中，现有但分散的测试结果存储库被锁定在纸质日志中，并且在全球微生物学实验室中构成了一个复杂但尚未开发的资源，用于跟踪微生物种群的出现，传播和进化传播。凭借在软件开发方面有四十年的经验来跟踪抗菌素抵抗的新兴趋势，我们在WHO WHO抗菌抗药性监视中心的团队波士顿与国家，地区和世界卫生组织总部协调，波士顿，波士顿，世界卫生组织。一直是动员和标准化此信息资源的领导者，以支持协调的科学研究和公共卫生行动。我们努力的基石是Whonet软件的开发和传播，这是一种灵活，精致，用户友好的工具，用于管理和分析微生物学测试结果。研究人员，微生物学家，临床医生，公共卫生流行病学家和国家监视协调员在90多个国家 /地区使用WHONET，主要是在本地和国家一级管理的，这是由1200多个临床，公共卫生，兽医，兽医，食品和学术实验室的影响。基础科学，临床和运营研究；公共卫生政策；临床决策支持；和实验室能力建设。该提案的目标是：a）为现有的Whonet软件提供持续的支持，同时集成了最新的适当信息技术，本体论和信息学标准； b）在爆发检测，数据可视化，自动化，通知和信息流中引入WHONET分析特征的显着增强功能以​​及； c）增加现有软件用户对WHONET的有效利用，将其使用扩展到新的技术和地理领域，并在协作研究网络中促进数据共享。这些事态发展将增强我们努力的科学和公共卫生影响，并促进合作研究开发和评估感染和抗菌耐药性遏制干预措施所需的战略基础设施。项目叙述：传染病，新确定的病原体和多药耐药微生物的持续出现是全球优先事项，它威胁着全球患者福利，并耗尽了有限的医疗保健资源。在90多个国家 /地区使用的Whonet软件为研究人员和公共卫生部门提供了用于跟踪感染和耐药性趋势的工具，并开发和评估遏制和控制的干预措施。该项目的目的是扩展在数据共享，爆发检测，警报通知以及公共卫生和科学监视网络中的协作研究领域。