Malaria Operations Research to Improve Malaria Control and Reduce Morbidity and Mortality in Malawi

疟疾行动研究旨在改善马拉维的疟疾控制并降低发病率和死亡率

• 批准号: 9899349
• 负责人: Don P Mathanga
• 金额: $ 10万
• 依托单位: UNIVERSITY OF MALAWI
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-31 至 2024-09-01
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9899349
• 关键词: Malaria; Operations; Research; Improve; Control

RFA-GH-19-015 College of Medicine Malaria Alert Center PROJECT SUMMARY Morbidity and mortality from malaria remains unacceptably high in Malawi, despite the scale up of various malaria control interventions. This high burden could be as a result of problems in 1) program implementation, 2) uptake and utilization of interventions, 3) absence of a proper program monitoring and evaluation and possibly 4) lack of relevant research to support the program. The College of Medicine Malaria Alert Centre is applying to undertake a cooperative agreement with the Centers for Disease Control and Prevention, USA to support the Malawi Ministry of Health’s efforts to reduce malaria related morbidity and mortality. This cooperative agreement proposal has five main objectives. Objective 1 consists of the conduct of malaria operational research and monitoring and evaluation activities in Malawi. The Ministry of Health has identified school children as a vulnerable group on top of under-five children and pregnant women - this is featured highly in this proposal. Objective 2 will develop and validate the impact of revised, enhanced or novel interventions that will contribute to effective malaria control in Malawi. Since there is a lot of co-morbidities in Malawi, objective 3 consists of supporting the Ministry of Health in translating the many operational research findings into policy whilst objective 4 and 5 will improve malaria surveillance systems and build capacity for these in the ministry respectively. In order to achieve these, a number of field and laboratory studies have been suggested. A number of monitoring and evaluation activities have also been proposed, including efforts to build capacity to evaluate the program. Most of the proposed activities are unique and relevant to the national and global malaria control agenda. The activities will be conducted in collaboration with the National Malaria Control Program, with technical support from the Centers for Disease Control and Prevention (USA) and other centers of excellence. This cooperation will build reasonable local capacity to undertake future malaria research on behalf of the Ministry of Health. Data and lessons learnt will be shared with the Ministry of Health, President Malaria Initiative (PMI), USAID and other malaria implementing partners for wider dissemination, to promote the implementation of evidence based malaria interventions.

RFA-GH-19-015 医学院疟疾警报中心 项目概要 尽管疟疾规模扩大，但马拉维的发病率和死亡率仍然高得令人无法接受 这种高负担可能是由于 1) 中的问题造成的。 计划实施，2) 干预措施的采用和利用，3) 缺乏适当的 计划监测和评估，可能 4) 缺乏相关研究来支持 医学院疟疾警报中心正在申请开展合作项目。 与美国疾病控制和预防中心达成协议，支持马拉维 卫生部为降低疟疾相关发病率和死亡率所做的努力。 协议提案有五个主要目标，目标 1 包括防治疟疾。 马拉维卫生部的业务研究以及监测和评估活动。 将学童视为除五岁以下儿童和孕妇之外的弱势群体 女性——这是本提案的重点内容，目标 2 将发展并验证其影响。 修订、加强或新颖的干预措施将有助于有效控制疟疾 马拉维 由于马拉维有很多合并症，目标 3 包括支持 卫生部将许多业务研究结果转化为政策，同时保持客观 4 和 5 将改善疟疾监测系统并建设该部的能力 分别。 为了实现这些目标，建议进行一些现场和实验室研究。 还提出了一些监测和评价活动，包括努力建立 评估计划的大多数活动都是独特的且与计划相关。 国家和全球疟疾控制议程将与以下机构合作开展。 国家疟疾控制计划，并得到疾病控制中心的技术支持 和预防（美国）与其他卓越中心的合作将建立合理的基础。 当地代表卫生部开展未来疟疾研究的能力。 将与卫生部、总统疟疾倡议 (PMI)、美国国际开发署分享经验教训 和其他疟疾实施伙伴进行更广泛的传播，以促进实施 基于证据的疟疾干预措施。