Targeted Healthcare Engineering for Systems Interventions in Stroke (THESIS)

中风系统干预的针对性医疗保健工程（论文）

• 批准号: 9902970
• 负责人: JANE Louise HOLL
• 金额: $ 62.5万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2023-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9902970
• 关键词: Targeted; Healthcare; Engineering; Systems; Interventions

Project Summary/Abstract Nearly 800,000 people in the United States each year are affected by stroke, which remains the leading cause of adult disability and 5th leading cause of death. Several proven medical and surgical treatments exist for acute stroke. However, diagnostic error and resultant treatment delays contribute to missed opportunities to reduce death and disability in acute stroke patients. Indiscriminate neurologic consultation and over-testing in the emergency department (ED) will stress and deplete currently available staff and resources and are not practical solutions. Furthermore, incomplete problem analysis and risk assessments can lead to unintended consequences of an intervention. Although recommendations and pathways exist for stroke evaluation and management, none has been systematically engineered, designed, or tested to identify and effectively address system failures especially in diagnostic error. The Targeted Healthcare Engineering for Systems Interventions in Stroke (THESIS) study will bring together dynamic learning laboratories consisting of stroke neurology, emergency medicine, informatics, engineering, and health services experts at 3 large, diverse healthcare systems in Chicago with experience in the application of systems engineering, problem analysis, design and development, implementation, and evaluation methods to identify and test solutions to reduce diagnostic error and resultant delays to evidence-based treatments for acute stroke patients in the ED.

项目概要/摘要 美国每年有近 80 万人受到中风影响，中风仍然是主要原因 成人残疾和第五大死亡原因。存在几种经过验证的药物和手术治疗方法 急性中风。然而，诊断错误和由此导致的治疗延误会导致错失治疗机会 减少急性中风患者的死亡和残疾。不加区别的神经科会诊和过度测试 急诊科 (ED) 将给现有的人员和资源带来压力并耗尽其资源，但 实用的解决方案。此外，不完整的问题分析和风险评估可能会导致意想不到的结果 干预的后果。尽管存在中风评估和治疗的建议和途径 管理方面，还没有经过系统的工程、设计或测试来识别和有效解决 系统故障，尤其是诊断错误。系统干预的有针对性的医疗保健工程 中风（论文）研究将汇集由中风神经学、 3 个大型多元化医疗保健机构的急诊医学、信息学、工程和健康服务专家 芝加哥系统，在系统工程应用、问题分析、设计和 开发、实施和评估方法来识别和测试解决方案以减少诊断错误 以及由此导致急诊科急性中风患者循证治疗的延误。