NRSA Training Core

NRSA 培训核心

• 批准号: 9511938
• 负责人: HENRY N GINSBERG
• 金额: $ 114.22万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9511938
• 关键词: Address; Adverse effects; Biomedical Research; Client satisfaction; Competence; Data Science; Discipline; Education; Effectiveness; Faculty; Genetic; Goals; Health; Healthcare; Human Resources; Institutes; Learning; Mentors; Methods; Molecular; Monitor; National Research Service Awards; Output; Patient Rights; Patients; Phenotype; Postdoctoral Fellow; Precision Medicine Initiative; Program Development; Research; Research Infrastructure; Research Personnel; Resources; Risk; Science; Students; TNFSF15 gene; Time; Training; Translating; United States National Institutes of Health; Universities; biomarker development; career; career development; clinical practice; cost; experience; faculty research; genomic data; human disease; implementation science; improved; improved outcome; innovation; member; novel; pre-doctoral; precision medicine; programs; skills

TL1 Precision Medicine Program Abstract Our goal is to establish the TRANSFORM TL1 Precision Medicine (PM) Program to provide training and mentoring in the methods and applications of PM to pre-docs, post-docs, junior faculty, and a wide range of research personnel. PM is the right treatment for the right patient at the right time; it offers the opportunity to increase effectiveness of health care at reduced cost with improved outcomes, decreased adverse effects, and greater patient satisfaction. Through a suite of innovative programs, we will enhance career development, translational capabilities, and collaborative skills of faculty and research team members from diverse disciplines around the theme of PM. Our goals are to: (i) develop innovative education and career development programs, building on and extending our many successful existing programs, that will build competency in our scholars and trainees to engage in interdisciplinary teamwork, make new discoveries, and translate those discoveries to clinical practice/patient benefit; (ii) demonstrate the effectiveness of those programs through continuous monitoring and assessment for quality improvement, using key metrics to evaluate the impact of our educational programs on research output, career trajectories, and continued engagement in biomedical research; and (iii) To disseminate findings on novel educational delivery approaches, new methods for assessing student learning, and best practices in enhancing interdisciplinary team science skills to our partners at Columbia, the members of the CTSA consortium, and educational programs throughout the nation. Columbia University is a significant contributor, nationally and world-wide, to research in genetics, genomics, data science, phenotyping and risk prediction, biomarker development, and the molecular basis of human disease; as well as to interdisciplinary team science training. These strengths will allow us to offer new and enhanced coursework in PM; create pre-doc and post-doc programs to increase competency in PM; develop short-term training that allows pre-docs to gain facility with PM strategies and methods; and evaluate our educational efforts in an ongoing way to improve programming. In 2013, Columbia's President, Lee Bollinger, announced the University-wide PM Initiative aimed at bringing together all units within Columbia to address the full spectrum of research, education, and implementation sciences in this field. Thus, this is the ideal time to undertake these goals. We are confident we can achieve these goals because of the outstanding CUMC research portfolio, the momentum provided by the new, University-wide PM initiative, our 10+ years of experience in administering successful training and mentoring programs, and the personnel and infrastructure provided by our Irving Institute resources. Through all these means, we are poised to contribute substantially to NIH's goal of building a larger and exceptionally well-prepared biomedical research workforce prepared to advance health through the potential of PM.

TL1 精准医学项目摘要 我们的目标是建立 TRANSFORM TL1 精准医学 (PM) 计划，提供培训和 向博士前、博士后、初级教师和广泛的人员提供 PM 方法和应用的指导 研究人员。 PM是在正确的时间为正确的患者提供正确的治疗；它提供了机会 以降低的成本提高医疗保健的有效性，改善结果，减少不良反应，以及 更高的患者满意度。通过一系列创新计划，我们将加强职业发展， 来自不同领域的教师和研究团队成员的转化能力和协作能力 围绕 PM 主题的学科。我们的目标是： (i) 发展创新教育和职业 发展计划，以我们许多成功的现有计划为基础并加以扩展，这将建立 我们的学者和实习生参与跨学科团队合作、做出新发现和 将这些发现转化为临床实践/患者利益； (ii) 证明这些措施的有效性 通过持续监控和评估质量改进来制定计划，使用关键指标 评估我们的教育计划对研究成果、职业轨迹和持续发展的影响 参与生物医学研究； (iii) 传播新颖教育方式的研究结果 方法、评估学生学习的新方法以及加强跨学科的最佳实践 向哥伦比亚大学的合作伙伴、CTSA 联盟的成员以及教育机构提供团队科学技能 全国各地的计划。哥伦比亚大学在国内和世界范围内做出了重大贡献 遗传学、基因组学、数据科学、表型和风险预测、生物标志物开发等领域的研究 人类疾病的分子基础；以及跨学科团队科学培训。这些优势 将使我们能够提供新的和增强的 PM 课程；创建博士前和博士后项目以增加 PM 能力；开展短期培训，使博士预科生能够熟悉 PM 策略和 方法;并持续评估我们的教育工作以改进编程。 2013年， 哥伦比亚大学校长 Lee Bollinger 宣布了全校范围内的 PM 倡议，旨在将所有学生聚集在一起 哥伦比亚大学内的各个单位致力于解决该领域的全方位研究、教育和实施科学问题 场地。因此，现在是实现这些目标的理想时机。我们有信心能够实现这些目标 由于 CUMC 出色的研究成果，新任大学校长所提供的动力 倡议，我们在管理成功的培训和指导计划方面拥有 10 多年的经验，以及 我们的欧文研究所资源提供的人员和基础设施。通过所有这些手段，我们 准备为 NIH 的目标做出重大贡献，即建立一个更大且准备充分的生物医学中心 研究人员准备通过 PM 的潜力促进健康。