A Tailored Cue-Card Driven HIV/STI Intervention for High Risk Groups Pilot Study

针对高危人群的定制提示卡驱动的 HIV/STI 干预试点研究

• 批准号: 7684928
• 负责人: WILLIAM A ZULE
• 金额: $ 22.27万
• 依托单位: RESEARCH TRIANGLE INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7684928
• 关键词: Acquired Immunodeficiency Syndrome; African American; Area; Behavior; Behavior Therapy; Biological Testing; Bisexual; Characteristics; Chlamydia; Computer Assisted; County; Crack Cocaine; Cues; Development; Disease; Drug usage; Drug user; Early treatment; Ensure; Epidemiologic Studies; Epidemiology; Ethnic Origin; Event; Female; Frequencies; Gender; Generic Drugs; Gonorrhea; HIV; Health Personnel; Health education; Hepatitis; Hepatitis B; Hepatitis C virus; Hispanics; Imprisonment; Injecting drug user; Intervention; Intervention Trial; Knowledge; Link; Methamphetamine; North Carolina; Participant; Pharmaceutical Preparations; Pilot Projects; Population Density; Powder dose form; Professional counselor; Provider; Randomized; Research; Resources; Risk; Risk Behaviors; Rural; Rural Health; Sampling; Services; Sexual Partners; Sexually Transmitted Diseases; Site; Staging; Subgroup; Syphilis; Test Result; Testing; Training; Translating; Treatment Efficacy; United States; Unsafe Sex; Woman; Work; brief intervention; cocaine use; comparison group; cost; design; genital herpes; group intervention; high risk; high risk sexual behavior; innovation; intervention effect; male; men who have sex with men; metropolitan; peer; public health relevance; rural area; sex; sex risk; success; transmission process; urban area; user-friendly

DESCRIPTION (provided by applicant): HIV and other sexually transmitted infections (STIs) are serious problems in many parts of the United States, including rural areas. While HIV risk groups in rural areas are similar to those in urban areas, the lower population density results in smaller numbers of most groups, such as injecting drug users (IDUs) and noninjecting drug users, sex workers, and men who have sex with men (MSM). Most health education materials and behavioral interventions are targeted to a specific audience or risk group and research has shown that interventions tailored to be gender specific and culturally sensitive are more effective than generic interventions. However, the small numbers of some of these groups in rural areas make it difficult for providers to justify the cost of maintaining staff and other resources that are needed to deliver interventions tailored to each demographic and risk group. The proposed study will draw from proven interventions to refine and pilot test a cue-card driven computer-assisted intervention that will be tailored to each participant's demographic characteristics, risk behaviors and biological test results. This intervention builds on our earlier intervention and epidemiological work with IDUs, crack users, sex workers, and MSM in rural and urban settings in which we found similar levels of HIV and other STIs in rural and urban areas. We also found that MSM, sex workers, IDUs and non-injecting drug users were all present, although in smaller numbers, in the rural areas. Therefore, we propose to pilot test the intervention in a medium-sized metropolitan area, where we have an urban field site to ensure that we have adequate numbers of participants in each risk group. Subsequently, we will assess the acceptability and feasibility of conducting the intervention in a rural setting, where we have also established a field site and presence. The proposed study will be conducted in three stages. The intervention will be refined during Stage 1, pilot tested in Stage 2, and the feasibility and acceptability of using the intervention in a rural area will be assessed in Stage 3. The specific aims of the proposed study are: 1. To refine a cue-card driven computer-assisted intervention that will be tailored to each participant's demographic characteristics (e.g. gender, ethnicity), risk behaviors and biological test results. 2. To pilot test the tailored intervention's effects on sexual risk behaviors (i.e., number of partners, frequency of unprotected sex) and drug use (e.g., frequency of use, frequency of use while having sex) and disease-specific knowledge (e.g., hepatitis B and C, genital herpes) using a two group randomized design with a generic intervention as a comparison group. 3. To assess the feasibility and acceptability of the tailored intervention in a rural setting. PUBLIC HEALTH RELEVANCE: The intervention that will be refined and pilot tested in this project may be very useful for reducing HIV and other sexually transmitted infections (STIs) and transmission and risk behaviors among high risk groups, particularly in rural areas. The intervention may also substantially reduce the burden on counselors that are responsible for providing multiple test results in settings where HIV, STI, and hepatitis testing and services are integrated.

描述（由申请人提供）：在包括农村地区在内的许多地方，艾滋病毒和其他性传播感染（性传播感染）是严重的问题。尽管农村地区的艾滋病毒风险群体与城市地区相似，但人口密度较低，大多数群体数量较小，例如注射吸毒者（IDU）和非注射吸毒者，性工作者以及与男性发生性关系的男性（MSM）。大多数健康教育材料和行为干预措施都是针对特定受众或风险组的，研究表明，量身定制的，量身定制为特定性别和文化敏感的干预措施比通用干预措施更有效。但是，在农村地区，其中一些群体中的一些群体使提供者难以证明维护员工和其他资源的成本是合理的，这些成本和其他资源是为每个人口统计和风险群体量身定制的干预措施。拟议的研究将从经过验证的干预措施中汲取精炼和试点测试，一种提示卡驱动的计算机辅助干预措施，该干预措施将针对每个参与者的人口统计学特征，风险行为和生物学测试结果量身定制。这种干预措施是基于我们在农村和城市环境中与IDU，Crack用户，性工作者以及MSM的早期干预和流行病学工作的基础，在该环境中，我们在农村和城市地区发现了类似水平的HIV和其他性传播感染。我们还发现，MSM，性工作者，IDU和非注射吸毒者都在场，尽管在农村地区的数量较小。因此，我们建议在中型大都市地区进行试验测试干预措施，在那里我们有一个城市场地，以确保我们在每个风险组中都有足够的参与者。随后，我们将评估在农村环境中进行干预的可接受性和可行性，在那里我们还建立了现场地点和存在。拟议的研究将分为三个阶段。 The intervention will be refined during Stage 1, pilot tested in Stage 2, and the feasibility and acceptability of using the intervention in a rural area will be assessed in Stage 3. The specific aims of the proposed study are: 1. To refine a cue-card driven computer-assisted intervention that will be tailored to each participant's demographic characteristics (e.g. gender, ethnicity), risk behaviors and biological test results. 2。用于测试量身定制的干预对性风险行为的影响（即，伴侣的数量，未经保护的性行为的频率）和吸毒（例如，使用频率，使用性频率，发生性别的使用频率）和特定于疾病的知识（例如，肝炎B和C，生殖器疱疹，生殖器疱疹，使用两组随机设计），使用一组一体的介入类似于一般的干预组。 3。评估在农村环境中定制干预的可行性和可接受性。 公共卫生相关性：该项目中将进行完善和试点测试的干预措施对于减少艾滋病毒和其他性传播感染（STI）以及高风险群体之间的传播和风险行为非常有用。干预措施还可以大大减轻负责在艾滋病毒，性传播感染和肝炎测试和服务的情况下提供多个测试结果的辅导员的负担。