Tanzanian Drug Treatment as AIDS Prevention - Reliability and Validity Study

坦桑尼亚药物治疗作为艾滋病预防 - 可靠性和有效性研究

• 批准号: 7756281
• 负责人: Mark L Williams
• 金额: $ 20.31万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-15 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7756281
• 关键词: AIDS prevention; Address; Africa South of the Sahara; Communities; Data; Development; Drug usage; Drug user; Europe; HIV; Heroin; Heroin Dependence; Hour; Injecting drug user; Injection of therapeutic agent; Intake; Interview; Knowledge; Measurement; Measures; Methods; Modification; Motivation; Needle Sharing; Needles; Outcome; Participant; Pharmaceutical Preparations; Phase; Preventive Intervention; Property; Psychometrics; Questionnaires; Readiness; Recommendation; Recruitment Activity; Reporting; Research; Research Project Grants; Sampling; Severities; Sex Behavior; Social Functioning; Structure; Tanzania; Testing; Time; Translating; Translations; Treatment outcome; United States; Validity and Reliability; Visit; Western Europe; addiction; base; design; drug efficacy; improved; innovation; meetings; programs; psychologic; public health relevance; response; social; standardize measure; transmission process; treatment program; vector

DESCRIPTION (provided by applicant): The purpose of this study, the Tanzanian Drug Treatment as HIV/AIDS Prevention Project (D-TAPP) - Reliability and Validity Study, is to conduct formative research necessary to the implement of drug treatment as an HIV prevention intervention in Dar es Salaam, Tanzania. The specific aims of D-TAPP 1) - Reliability and Validity Study are: Aim1: To develop culturally appropriate measures of psychological functioning, social functioning, treatment motivation, addiction severity, and readiness for treatment; Aim 2: To assess IDUs' understanding and relevancy of the measures of psychological functioning, social functioning, treatment motivation, addiction severity, and readiness for treatment; and Aim 3: To test the reliability and validity of the D-TAPP Questionnaire. The D-TAPP - Reliability and Validity Study will be implemented in three components reflecting the three specific aims using a mixed methods design. In component 1, the D-TAPP questionnaire will be translated from English to Swahili and the accuracy of the translations and the content validity of the translated measures will be assessed by a panel of native Swahili-speaking experts. In component 2, semi-structured interview data will be collected from a purposeful sample of 40 IDUs. In this component, the D-TAPP questionnaire will be presented to IDU participants, and they will be asked to assess the understandability and cultural relevancy of each item in the questionnaire (Aim 2). Participants will also be asked to evaluate scales used to record measurement responses. In particular, IDUs will be asked to make recommendations that will improve understandability, cultural relevancy, and response measurement. The questionnaire will be modified to reflect findings produced by the Component 2 study. Component 3 will assess the psychometrics of the measures. Internal and 48 hour test/retest reliability will be determined along with content, construct and criterion related validities. For this study, a purposeful sample of 150 IDUs will be recruited to participate. Data will be collected at intake and 48 hours later. PUBLIC HEALTH RELEVANCE: Tanzanian Drug Treatment as HIV/AIDS Prevention Project (D-TAPP) - Reliability and Validity Study will investigate the psychometric properties of standardized measures of treatment motivation in a sample of Tanzanian injection drug users.

描述（由申请人提供）：本研究的目的，坦桑尼亚药物治疗作为艾滋病毒/艾滋病预防项目（D -TAPP） - 可靠性和有效性研究，是在坦桑尼亚达萨尼亚达累斯萨拉姆（Dar Es Salaam）实施药物治疗所必需的形成性研究。 D -TAPP的具体目的1） - 可靠性和有效性研究是：AIM1：开发适当的心理功能，社会功能，治疗动机，成瘾的严重程度和治疗准备的措施；目的2：评估IDUS对心理功能，社会功能，治疗动机，成瘾的严重程度和治疗准备的理解和相关性；和目标3：测试D-TAPP问卷的可靠性和有效性。 D -TAPP - 可靠性和有效性研究将在三个组件中实施，以使用混合方法设计来反映三个特定目的。在组件1中，D-TAPP问卷将从英语翻译成斯瓦希里语，翻译的准确性和翻译措施的内容有效性将由一组讲斯瓦希里语的专家进行评估。在组件2中，将从有目的的40个IDU样本中收集半结构化访谈数据。在此组成部分中，将向IDU参与者介绍D-TAPP问卷，并将要求他们评估问卷中每个项目的可理解性和文化相关性（AIM 2）。还将要求参与者评估用于记录测量响应的量表。特别是，将要求IDU提出建议，以改善可理解性，文化相关性和响应量度。调查表将进行修改，以反映由组件2研究产生的发现。组件3将评估措施的心理计量学。内部和48小时的测试/重新测试可靠性将与内容，构造和标准相关的有效性一起确定。对于这项研究，将招募有目的的150个IDU样本参加。数据将在摄入量和48小时后收集。公共卫生相关性：坦桑尼亚药物治疗作为艾滋病毒/艾滋病预防项目（D -TAPP） - 可靠性和有效性研究将研究坦桑尼亚注射药物使用者样本中标准化治疗动机的心理测量特性。