Tanzania Injection Drug Use/HIV Prevention Project

坦桑尼亚注射吸毒/艾滋病毒预防项目

• 批准号: 6892578
• 负责人: Mark L Williams
• 金额: $ 17.16万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-03-01 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6892578
• 关键词: AIDS education /prevention; Africa; behavioral /social science research tag; clinical research; communicable disease transmission; condoms; data collection methodology /evaluation; dyadic interaction; enzyme linked immunosorbent assay; high risk behavior /lifestyle; human subject; hypodermic needle; intravenous drug abuse; needle sharing; psychosocial separation; questionnaires; safe sex /sex abstinence; sex behavior; socioenvironment; substance abuse related behavior; urban area; western blottings

The contribution made by injection drug use to the HIV/AIDS pandemic in sub-Saharan Africa has received little scientific attention. The "TANZANIAN AIDS PREVENTION PROJECT, (TAPP)," will investigate injection drug use in Sub-Saharan African. TAPP builds on research we have been conducting for the past two years in Dar es Salaam, Tanzania. Our studies strongly suggest that injection drug use may be a significant contributor to the AIDS pandemic in Africa, especially in urban areas. TAPP has six specific aims. They are: to describe the environmental barriers to and facilitators of safer needle use and sexual practices; to describe the nuances of needle sharing and sexual practices within dyad structures; to describe the effect of social stigma as a barrier to acceptability of HTV testing and educational activities; to estimate HTV prevalence among drug injectors in Dar es Salaam; to estimate the prevalence of safe/unsafe needle use and safe/unsafe sexual behaviors within dyad structures; and to estimate safer needle use and condom use intentions within dyad structures. We will accomplish these aims using a mixed method research design composed of qualitative and quantitative components. Data collection will be guided by the Social Cognitive Theory. Data will be collected from purposeful samples of injection drug users residing in seven neighborhoods in Dar es Salaam. The two components of the mixed design are complementary, each producing data that, when triangulated, will provide a rich assessment of the HTV injection drug risk environment, prevalence of HTV among injection drug users, and sufficient social cognitive data to guide the development of interventions to decrease HTV incidence related to injection drug use that are relevant to the Tanzanian context.

注射药物使用对撒哈拉以南非洲艾滋病毒/艾滋病大流行的贡献很少受到科学关注。 “坦桑尼亚艾滋病预防项目（TAPP）”将调查撒哈拉以南非洲的注射药物使用。 TAPP建立在我们过去两年中在坦桑尼亚达累斯萨拉姆（Dar Es Salaam）进行的研究。我们的研究强烈表明，注射药物的使用可能是非洲，尤其是在城市地区的艾滋病大流行的重要贡献。 Tapp有六个具体目标。它们是：描述使用和性行为更安全的环境障碍和促进者；描述二元结构内针和性实践的细微差别；描述社会污名作为HTV测试和教育活动可接受性的障碍；估计达累斯萨拉姆药物注射器之间的HTV患病率；估计二元组结构内安全/不安全的针头使用和安全/不安全的性行为的流行；并估算二元组结构内的更安全的针头使用和避孕套意图。我们将使用由定性和定量组成部分组成的混合方法研究设计来实现这些目标。数据收集将以社会认知理论为指导。数据将从有目的的注射吸毒者样本中收集，这些注射用户居住在达累斯萨拉姆的七个社区。混合设计的两个组成部分是互补的，每个组成部分都会产生数据，这些数据将在三角策略时，将对HTV注入药物风险环境，注射药物使用者中HTV的流行以及足够的社会认知数据进行丰富的评估，并指导干预措施的发展，以开发与HTV药物使用相关的HTV患者与Tanzanian相关的HTV药物使用。