Neurobehavioral predictors of diet adherence

饮食依从性的神经行为预测因素

• 批准号: 7677216
• 负责人: Bradley M. Appelhans
• 金额: $ 7.85万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-03-01 至 2009-09-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7677216
• 关键词: Accounting; Address; Adherence; Adult; Affect; Behavioral; Behavioral Assay; Behavioral Sciences; Body Weight decreased; Cessation of life; Counseling; Coupled; Development; Diet; Diet Modification; Dietary Intervention; Eating; Eating Behavior; Energy Intake; Energy Metabolism; Etiology; Fatty acid glycerol esters; Feeding behaviors; Food; Goals; Guidelines; Human; Hunger; Individual; Individual Differences; Intake; Malignant Neoplasms; Measures; Metabolic; Methods; Minority; Modeling; Neurosciences; Nutritional; Obesity; Obesity associated cancer; Overweight; Participant; Patient Self-Report; Pattern; Play; Population; Prevalence; Prevention; Principal Investigator; Process; Property; Publishing; Recommendation; Records; Research; Rewards; Risk; Role; Sampling; Series; Smoking; Taste Perception; Testing; Theoretical model; Weight; Woman; abstracting; cancer prevention; computerized; discount; discounting; food consumption; fruits and vegetables; innovation; mortality; neurobehavioral; novel strategies; pleasure; prevent; psychologic; response; saturated fat; statistics; weight loss intervention

Project Summary/Abstract Overweight and obesity account for 8-17% of all cancers in adults, and the increasing prevalence of overweight and obesity in the US over the past 3 decades poses a major challenge to cancer prevention efforts. Dietary modification will be necessary to achieve weight loss at the population level, but studies have shown that only a small minority of dieters successfully maintain meaningful weight loss beyond one year of starting a diet. Though weight loss is affected by many factors, poor behavioral adherence to nutritional targets appears to be the foremost obstacle to weight loss. Therefore, the objective of this project is to identify psychological and behavioral factors that undermine individuals' abilities to adhere to a weight loss diet. Mounting evidence from the fields of neuroscience and behavioral science indicates that the pleasure and reward associated with palatable food play a substantial role in the etiology of obesity and may interfere with the ability to refrain from palatable, energy-dense foods while dieting. We will determine whether the degree to which individuals respond psychologically to the immediately rewarding effects of palatable food predicts the ability to adhere to a weight loss diet. Eighty-five healthy, overweight or obese women will complete behavioral and self-report measures quantifying sensitivity to the rewarding effects of food. Participants will then receive nutritional counseling and be asked to follow an energy expenditure-adjusted weight loss diet. Nutritional analysis of weighed food records will be performed to determine adherence to individualized nutritional targets for energy, fruit, vegetable, and saturated fat intake. Statistical analyses will test the proposed associations between psychological responses to immediate food reward and diet adherence. The expected pattern of findings would highlight the need to address reward-driven eating in interventions for weight loss and cancer prevention.

项目摘要/摘要超重和肥胖占成年人所有癌症的8-17％，并且在过去30年中，美国超重和肥胖的患病率不断增加，这对预防癌症的工作构成了重大挑战。在人口水平上实现体重减轻将是必要的，但是研究表明，只有少数饮食者能够成功地维持有意义的体重减轻，超过一年的饮食。尽管体重减轻受许多因素的影响，但对营养目标的行为依从性较差似乎是减肥的首要障碍。因此，该项目的目的是确定破坏个人遵守减肥饮食能力的心理和行为因素。来自神经科学和行为科学领域的越来越多的证据表明，与可口的食物相关的愉悦和奖励在肥胖症的病因中起着重要作用，并且可能会干扰避免节食时避免使用可口的，能量浓的食物的能力。我们将确定个人在心理上对可口食品的立即奖励效果做出心理反应的程度可以预测遵守减肥饮食的能力。八十五名健康，超重或肥胖的妇女将完成行为和自我报告措施量化对食物奖励效果的敏感性。然后，参与者将接受营养咨询，并要求遵循通过能源支出调整的减肥饮食。将对称重的食物记录进行营养分析，以确定遵守个性化的营养目标，以摄取能量，水果，蔬菜和饱和脂肪的摄入量。统计分析将测试对立即食物奖励和饮食依从性的心理反应之间提出的关联。预期的发现模式将强调需要解决以减肥和预防癌症的干预措施中奖励驱动的饮食。