Milwaukee Clinical Site Hub

密尔沃基临床中心中心

• 批准号: 7417540
• 负责人: TOM Paul AUFDERHEIDE
• 金额: $ 19.41万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-03 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7417540
• 关键词: Accident and Emergency department; Acute; Adult; Appendix; Architecture; Area; Award; Cardiac; Caring; Childhood; Clinical; Clinical Research; Clinical Trials; Collaborations; Commit; Communities; Community Health; Community Hospitals; Contracts; County; Critical Care; Data; Emergency Medicine; Emergency Situation; Emergency medical service; Emergency treatment; Enrollment; Faculty; Foundations; Funding; Future; Goals; Health Personnel; Health Services Research; Hospital Departments; Hospital Units; Hospitals; Housing; Human Resources; Informed Consent; Institution; Intervention Studies; Joint Commission on Accreditation of Healthcare Organizations; Leadership; Medical; Medical Records; Medicine; Methods; Modeling; Monitor; Neurologic; Neurological emergencies; Neurology; Neurosciences; Outcome; Paramedical Personnel; Patient Recruitments; Patients; Pediatric Hospitals; Pediatric Surgical Procedures; Physical Medicine; Principal Investigator; Protocols documentation; Qualifying; Radiology Specialty; Range; Recruitment Activity; Research; Research Ethics Committees; Research Infrastructure; Research Personnel; Research Support; Resources; Resuscitation; Site; Specialist; Stroke; System; Telemedicine; Testing; Time; Training Activity; Trauma; Wisconsin; base; clinical research site; college; cost; dissemination research; experience; human subject; innovation; interest; member; nervous system disorder; neurosurgery; pediatric trauma; professor; programs; trauma centers; treatment trial

DESCRIPTION (provided by applicant): The Department of Emergency Medicine of Froedtert Memorial Lutheran Hospital (FMLH) in collaboration with the Medical College of Wisconsin (MCW), and the Children's Hospital of Wisconsin are submitting this application for consideration to become a Clinical Site Hub (CSH) of the NINDS Emergencies Treatment Trials Network (NETT)(RFA-NS-06-009), to be known as the Milwaukee Clinical Site Hub (MCSH). Implementation of the selected NETT Network protocols will exploit the award-winning models of the Milwaukee County Emergency Medical Services (EMS) System and the nationally recognized Adult and Pediatric Trauma Centers housed at FMLH Adult Emergency Department and the adjoining Children's Hospital of Wisconsin (CHW) Pediatric Emergency Department, located on the MCW campus. Froedtert Memorial Lutheran Hospital, the Froedtert-MCW Stroke and Neurovascular Center, the Children's Hospital of Wisconsin, and the Milwaukee County EMS System will serve as the foundation of the Milwaukee Hub. Eight of the area's 15 affiliated paramedic-receiving community hospitals will serve as clinical spokes to support patient assessment and recruitment in real time and facilitate the dissemination of research results. These hospitals are members of the Milwaukee Emergency Medicine Research Consortium (MEMRC), an experienced and proven research association, distinguished by its long-standing infrastructure to support in- hospital and out-of-hospital research. The Milwaukee HUB will capitalize on its enormous existing research infrastructure to cost-effectively achieve the goals of the NETT to provide clinical leadership, research support, and local neurological expertise; coordinate IRB activities and human subjects protections; enter data, manage contracts, and oversee training activities. The principal investigator and key personnel are committed to actively partnering with the NETT Network and to disseminating the outcomes of the collective activities among community health care providers. The Milwaukee HUB aims to: 1) Leverage our existing infrastructure, established collaborations, and experience in conducting clinical research in the EMS and hospital settings (including exception to informed consent under emergency circumstances) to perform selected NETT clinical trials to enhance the efficient conduct of clinical research in neurological emergencies; 2) Orchestrate the participation of multiple emergency medicine departments and hospitals to expedite patient recruitment in neurological studies; 3) Engage a wide spectrum of investigators from MCW and participating hospitals; 4) Maximize our successful experience and capacity to recruit and retain a broad range of qualified subjects; 5) Cooperate with other NETT Hubs in facilitating the transfer of research; and 6) Coordinate with Network members in developing and testing innovative telemedicine methods involving off-site specialists in the care of neurological disorders in the emergency department.

描述（由申请人提供）：与威斯康星州医学院（MCW）合作，弗罗德特纪念馆路德医院（FMLH）的急诊医学系和威斯康星州儿童医院正在提交此申请，以成为临床现场枢纽（CSH）的临床现场枢纽（CSH）密尔沃基临床站点中心（MCSH）。选定的NetT网络协议的实施将利用密尔沃基县紧急医疗服务（EMS）系统的屡获殊荣模型以及位于FMLH成人急诊室的全国认可的成人和儿科创伤中心，以及位于MCW Campus的毗邻的Wisconsin（CHW）儿童医院（CHW）儿童医院（CHW）儿童医院（CHW）。 Froedtert Memorial Lutheran医院，Froedtert-MCW中风和神经血管中心，威斯康星州儿童医院和密尔沃基县EMS系统将作为密尔沃基枢纽的基础。该地区的15个附属护理人员接收社区医院中有8家将作为临床辐条，以实时支持患者评估和招聘，并促进研究结果的传播。这些医院是密尔沃基急诊医学研究联盟（MEMRC）的成员，该联盟（MEMRC）是一家经验丰富且经验丰富的研究协会，其特有的是其长期的基础设施，以支持医院和院外研究。密尔沃基枢纽将利用其庞大的现有研究基础设施，以成本效益地实现Nett的目标，以提供临床领导，研究支持和当地神经学专业知识；协调IRB活动和人类受试者的保护；输入数据，管理合同并监督培训活动。首席调查员和主要人员致力于积极与NetT网络合作，并传播社区卫生保健提供者之间集体活动的结果。密尔沃基枢纽的目的是：1）利用我们现有的基础设施，建立合作和经验在EMS和医院环境进行临床研究（包括在紧急情况下同意下的例外）来进行选定的NETT临床试验，以增强神经系统紧急情况临床研究的有效进行； 2）策划多个急诊医学部门和医院的参与，以加快患者招募神经学研究； 3）参与MCW和参与医院的各种各样的调查员； 4）最大化我们成功的经验和能力，可以招募和保留广泛的合格受试者； 5）与其他NetT中心合作，以促进研究的转移； 6）与网络成员协调开发和测试创新的远程医疗方法，该方法涉及现场专家，以护理急诊科的神经系统疾病。