Methodology Core

方法论核心

• 批准号: 7267287
• 负责人: ROWLAND W CHANG
• 金额: $ 31.92万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2012-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7267287
• 关键词: Methodology; Core

The Methodology and Data Management Core has been critically important to the success of the Northwestern University MAMDC and the current MCRC and is critically important to this renewal. The centralized availability of expertise in database and study form construction; data entry, monitoring, and retrieval; and the various analytic techniques used to test hypotheses and control for potential confounders are essential resources for both established and new investigators. The Core has assisted educators, epidemiologists, and health services researchers from several divisions and departments in studying a wide variety of disease and demographic groups including systemic lupus erythematosus, osteoarthritis, juvenile dermatomyositis (JDMS), rheumatoid arthritis, and the elderly. Core resources have been used efficiently because of the economies of scale. Recognizing that newer analytic techniques have become available and more accepted in the medical literature, this proposal continues the expansion of our work in clinical epidemiology and health services research previously implemented. Given this Center's emphasis on longitudinal outcomes research, experts in advanced statistical techniques (generalized estimating equations (GEE), classification and regression trees (CART), discrete Cox regression analysis, meta-analysis), economics, decision analysis, clinical epidemiology , behavioral science and genetics are included as Core investigators. The Core will support the three full proposals and the one developmental/feasibility proposal in this grant application and the funded activities. It will continue to contribute to the MCRC research environment by providing data management and methodologic assistance to investigators who engage in arthritis related research. The participation of Core investigators in the arthritis clinical research conference and enhanced viability and support for clinical epidemiology, health services research, behavioral science, and genetics on Northwestern University's Chicago Campus further heighten the Core's influence on the environment.

方法和数据管理核心对成功的成功至关重要 西北大学MAMDC和当前的MCRC，对这种续约至关重要。这 集中的数据库和研究形式的专业知识；数据输入，监视和 检索；以及用于检验假设和控制潜在混杂因素的各种分析技术 对于已建立和新调查人员来说是必不可少的资源。核心已协助教育者， 流行病学家和来自多个部门和部门的卫生服务研究人员研究广泛 各种疾病和人口组，包括全身性红斑狼疮，骨关节炎，少年 皮肌炎（JDMS），类风湿关节炎和老年人。核心资源已有效地使用 由于规模经济。 认识到较新的分析技术已在医疗中获得并更加接受 文献，该建议继续扩大我们在临床流行病学和卫生服务方面的工作 以前实施的研究。鉴于该中心强调纵向结果研究，专家 在先进的统计技术（广义估计方程（GEE），分类和回归中 树木（购物车），离散的COX回归分析，荟萃分析），经济学，决策分析，临床 流行病学，行为科学和遗传学被包括为核心研究人员。核心将支持 本赠款申请中的三个完整建议和一个发展/可行性建议和 资助的活动。它将通过提供数据来继续为MCRC研究环境做出贡献 对参与关节炎相关研究的研究人员的管理和方法学帮助。这 核心研究人员参加关节炎临床研究会议，并增强生存能力和 支持临床流行病学，卫生服务研究，行为科学和遗传学 西北大学的芝加哥校园进一步增强了核心对环境的影响。