ACTIVITY 3: TROPICAL INFECTIOUS DISEASES DETECTION AND PREVENTION

活动 3：热带传染病检测和预防

• 批准号: 7715310
• 负责人: Duane J Gubler
• 金额: $ 71.96万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7715310
• 关键词: Acquired Immunodeficiency Syndrome; Applied Research; Asia; Asians; Clinical; Communicable Diseases; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Country; Detection; Diagnostic tests; Disease; Disease Outbreaks; Economics; Emerging Communicable Diseases; Funding; Grant; Histology; Institutes; Institution; Link; Methods; Morbidity - disease rate; Pathogen detection; Pathogenesis; Prevention; Public Health; Reagent; Research; Research Personnel; Resources; Sentinel; Source; Support of Research; System; Technology; Translational Research; Transportation; Tropical Medicine; United States; United States National Institutes of Health; Vaccines; improved; innovation; molecular pathology; mortality; pandemic disease; pathogen; programs; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Regarding AIDS: Tropical infectious diseases are among the most important public health problems facing most countries in the Asia-Pacific Region, and pose a major cause of morbidity and mortality, as well as crippling economic loss. The Tropical Infectious Diseases Detection and Prevention Core (TIDDPC) is an integral component of the Asia-Pacific Institute of Tropical Medicine and Infectious Diseases (APITMID), which provides a much-needed additional resource to help build a vigorous clinical and translational science program, focusing on developing improved diagnostic tests, rapid and accurate disease-detection systems, innovative treatments, vaccines and other prevention tools and strategies. The central hypothesis is that globalization and modern transportation, combined with demographic and societal changes in Asian countries, will result in more zoonotic disease agents jumping species and causing increasingly frequent outbreaks of diseases having potential of pandemic spread. Thus the establishment of research pre-eminence in tropical infectious diseases as UHM would provide a valuable link in an early-warning sentinel network for the continental United States on new, emerging and re-emerging infectious diseases. The specific aims of this RCMI-funded research core are to 1) develop a Pathogen Reference and Reagent Core Facility to support basic and applied research on new, emerging and re-emerging tropical infectious diseases; 2) develop a Molecular Pathology and Histology Core Facility to support research on new detection methods and pathogenesis of infectious diseases; and 3) develop a Microarray Core Facility to support pathogenesis-related research and assist in developing rapid pathogen-detection and pathogen-discovery technology.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 关于艾滋病： 热带传染病是亚太地区大多数国家面临的最重要的公共卫生问题之一，构成了发病率和死亡率的主要原因以及经济损失。 The Tropical Infectious Diseases Detection and Prevention Core (TIDDPC) is an integral component of the Asia-Pacific Institute of Tropical Medicine and Infectious Diseases (APITMID), which provides a much-needed additional resource to help build a vigorous clinical and translational science program, focusing on developing improved diagnostic tests, rapid and accurate disease-detection systems, innovative treatments, vaccines and other prevention tools and策略。中心假设是，全球化和现代运输，加上亚洲国家的人口统计和社会变化，将导致更多的人畜共患病毒跳跃物种，并导致越来越频繁的疾病爆发具有大流行蔓延的潜力。因此，在热带传染病中建立研究前的研究前，因为UHM将在美国大陆的早期警告前哨网络中为新的，新兴和重新出现的感染性疾病提供宝贵的联系。该RCMI资助的研究核心的具体目的是1）开发病原体参考和试剂核心设施，以支持有关新，新兴和重新出现热带传染病的基本和应用研究； 2）开发一种分子病理学和组织学核心设施，以支持有关新检测方法的研究和传染病的发病机理； 3）开发一个微阵列核心设施，以支持发病机理相关的研究并有助于开发快速的病原体检测和病原体发现技术。