ACTIVITY 3: TROPICAL INFECTIOUS DISEASES DETECTION AND PREVENTION

活动 3：热带传染病检测和预防

• 批准号: 8357173
• 负责人: VIVEK Ramchandra NERURKAR
• 金额: $ 40.71万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-16 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357173
• 关键词: Acquired Immunodeficiency Syndrome; Applied Research; Asia; Asians; Basic Science; Clinical Sciences; Communicable Diseases; Core Facility; Country; Detection; Diagnostic tests; Disease; Disease Outbreaks; Economics; Emerging Communicable Diseases; Funding; Grant; Infection; Institutes; Link; Methods; Morbidity - disease rate; National Center for Research Resources; Pathogen detection; Pathogenesis; Prevention; Principal Investigator; Public Health; Reagent; Research; Research Infrastructure; Research Support; Resources; Sentinel; Source; System; Technology; Translational Research; Transportation; Tropical Medicine; United States; United States National Institutes of Health; Vaccines; cost; improved; infrastructure development; innovation; molecular pathology; mortality; pandemic disease; pathogen; programs; success; tool; vector; Acquired Immunodeficiency Syndrome; Applied Research; Asia; Asians; Basic Science; Clinical Sciences; Communicable Diseases; Core Facility; Country; Detection; Diagnostic tests; Disease; Disease Outbreaks; Economics; Emerging Communicable Diseases; Funding; Grant; Infection; Institutes; Link; Methods; Morbidity - disease rate; National Center for Research Resources; Pathogen detection; Pathogenesis; Prevention; Principal Investigator; Public Health; Reagent; Research; Research Infrastructure; Research Support; Resources; Sentinel; Source; System; Technology; Translational Research; Transportation; Tropical Medicine; United States; United States National Institutes of Health; Vaccines; cost; improved; infrastructure development; innovation; molecular pathology; mortality; pandemic disease; pathogen; programs; success; tool; vector

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Regarding AIDS Tropical infectious diseases are among the most important public health problems facing most countries in the Asia-Pacific region, and pose a major cause of morbidity and mortality, as well as crippling economic loss. The Tropical Infectious Diseases Detection and Prevention Core (TIDDPC) is an integral component of the Asia-Pacific Institute of Tropical Medicine and Infectious Diseases (APITMID), which provides a much-needed additional resource to help build a vigorous clinical and translational science program, focusing on developing improved diagnostic tests, rapid and accurate disease-detection systems, innovative treatments, vaccines and other prevention tools and strategies. The central hypothesis is that globalization and modern transportation, combined with demographic and societal changes in Asian countries, will result in more vector-borne infections, as well as zoonotic disease agents jumping species, causing increasingly frequent outbreaks of diseases having the potential of pandemic spread. Thus, the establishment of research pre-eminence in tropical infectious diseases at UHM would provide a valuable link in an early-warning sentinel network on new, emerging and re-emerging infectious diseases for the continental United States. The specific aims of this RCMI-funded research core are to 1) develop a Pathogen Reference and Reagent Core Facility to support basic and applied research on new, emerging and re-emerging tropical infectious diseases; 2) develop a Molecular Pathology Core Facility to support research on new detection methods and pathogenesis of infectious diseases; and 3) develop a Microarray Core Facility to support pathogenesis-related research and assist in developing rapid pathogen-detection and pathogen-discovery technology.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 关于艾滋病 热带传染病是亚太地区大多数国家面临的最重要的公共卫生问题之一，构成了发病率和死亡率的主要原因以及经济损失。 The Tropical Infectious Diseases Detection and Prevention Core (TIDDPC) is an integral component of the Asia-Pacific Institute of Tropical Medicine and Infectious Diseases (APITMID), which provides a much-needed additional resource to help build a vigorous clinical and translational science program, focusing on developing improved diagnostic tests, rapid and accurate disease-detection systems, innovative treatments, vaccines and other prevention tools and策略。中心假设是，全球化和现代运输，加上亚洲国家的人口统计和社会变化，将导致更多的媒介传播感染，以及人畜共患病毒剂跳跃物种，从而导致越来越频繁地爆发具有大流行潜力的疾病。因此，在UHM的热带传染病中建立研究前的研究将在美国大陆的新，新兴和重新出现的新兴，新兴和重新出现的传染病的早期哨兵网络中提供宝贵的联系。该RCMI资助的研究核心的具体目的是1）开发病原体参考和试剂核心设施，以支持有关新，新兴和重新出现热带传染病的基本和应用研究； 2）开发一种分子病理学核心设施，以支持有关新检测方法的研究和传染病的发病机理； 3）开发一个微阵列核心设施，以支持发病机理相关的研究并有助于开发快速的病原体检测和病原体发现技术。