CORE D: BIOINFORMATICS CORE

核心 D：生物信息学核心

• 批准号: 7715336
• 负责人: JAMES M BOWER
• 金额: $ 34.48万
• 依托单位: UNIVERSITY OF TEXAS SAN ANTONIO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7715336
• 关键词: Bioinformatics; Biological; Class; Complex; Computational Biology; Computer Retrieval of Information on Scientific Projects Database; Computer software; Core Facility; Funding; Future; Genome; Grant; Human Resources; Institution; Modeling; Range; Regulation; Research; Research Infrastructure; Research Personnel; Resources; Source; Students; Support of Research; Training; United States National Institutes of Health; design; protein expression

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A. Specific Aims The overall objective of the proposed Core in Computational Biology and Bioinformatics is to provide a world-class facility supporting the research of current as well as future biologists at UTSA as well as the training of our students. The two specific aims identified in the original proposal were to 1) Establish a Bioinformatics core facility and 2) Support Computational Biology. The Computational Biology / Bioinformatics Facility we are constructing with funding from the RCMI, is designed as to support a range of research from sophisticated study of genomes, to analysis of the dynamics of the regulation, control and expression of proteins, to increasing complex efforts to construct models at all levels of biological organization. While the software, hardware and personnel involved in supporting each activity are somewhat different  the essential infrastructure requirements for each are shared, and are therefore described together in the following sections:

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 A. 具体目标 拟议的计算生物学和生物信息学核心的总体目标是提供世界一流的设施，支持 UTSA 当前和未来生物学家的研究以及学生的培训。 最初提案中确定的两个具体目标是 1) 建立生物信息学核心设施和 2) 支持计算生物学。我们正在 RCMI 的资助下建设计算生物学/生物信息学设施，旨在支持一系列研究，从基因组的复杂研究，到蛋白质调节、控制和表达的动态分析，再到增加复杂的努力构建生物组织各个层面的模型。 虽然支持每项活动所涉及的软件、硬件和人员有所不同，但每项活动的基本基础设施要求是相同的，因此在以下各节中一起进行描述：