CORE D: BIOINFORMATICS CORE

核心 D：生物信息学核心

• 批准号: 7561556
• 负责人: JAMES M BOWER
• 金额: $ 33.19万
• 依托单位: UNIVERSITY OF TEXAS SAN ANTONIO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7561556
• 关键词: Bioinformatics; Biological; Class; Complex; Computational Biology; Computer Retrieval of Information on Scientific Projects Database; Computer software; Core Facility; Funding; Future; Genome; Grant; Human Resources; Institution; Modeling; Range; Regulation; Research; Research Infrastructure; Research Personnel; Resources; Source; Students; Support of Research; Training; United States National Institutes of Health; design; protein expression

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A. Specific Aims The overall objective of the proposed Core in Computational Biology and Bioinformatics is to provide a world-class facility supporting the research of current as well as future biologists at UTSA as well as the training of our students. The two specific aims identified in the original proposal were to 1) Establish a Bioinformatics core facility and 2) Support Computational Biology. The Computational Biology / Bioinformatics Facility we are constructing with funding from the RCMI, is designed as to support a range of research from sophisticated study of genomes, to analysis of the dynamics of the regulation, control and expression of proteins, to increasing complex efforts to construct models at all levels of biological organization. While the software, hardware and personnel involved in supporting each activity are somewhat different  the essential infrastructure requirements for each are shared, and are therefore described together in the following sections:

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 A.具体目标 拟议的核心在计算生物学和生物信息学方面的总体目标是提供世界一流的设施，以支持UTSA当前以及未来生物学家的研究以及对学生的培训。 原始建议中确定的两个具体目的是1）建立生物信息学核心设施和2）支持计算生物学。我们正在通过RCMI资助来构建的计算生物学 /生物信息学设施，旨在支持一系列从基因组的复杂研究到分析蛋白质调节，控制和表达的动态，到在所有水平生物学组织中构建模型的复杂努力的分析。 尽管支持每个活动的软件，硬件和人员与每个活动有所不同，但共享每个活动的基本基础架构要求，因此在以下各节中一起描述：